Doç. Dr. METİN YILDIRIM

1. Design and synthesis of benzimidazolium–chalcone salts with multitarget biological activity: Experimental, computational, and gene expression studies

YILDIRIM M., Ünver H., Necip A., Cimentepe M., Cimentepe Ö. Ö., Demirbag B., et al.

Journal of Molecular Structure , cilt.1367, 2026 (SCI-Expanded, Scopus)

2. Synthesis and Biological Evaluation of Schiff Base Derivatives Exhibiting Antimicrobial, Antifungal, and Antibiofilm Activities Supported by Molecular Docking

Yilmaz Ö., Akdoğan M., Çevik P. K., YILDIRIM M.

ChemistrySelect , cilt.11, sa.14, 2026 (SCI-Expanded, Scopus)

3. Pomegranate hydrochar and tamanu oil-enriched chitosan-PF127 hydrogel: antimicrobial efficacy against multidrug-resistant bacteria

Yildirim M., Yabalak E., Dogan K., Cimentepe M., ÖZTÜRK G.

Polymer Bulletin , cilt.83, sa.4, 2026 (SCI-Expanded, Scopus)

4. Design, Synthesis, In Vitro and Molecular Docking Evaluation of Triphenylphosphonium-Hydrazone Hybrids Against MDR Bacteria, AChE, and Laryngeal Cancer (Hep-2)

Yildirim M., Ünver H., Necip A., Çimentepe M., Erşatır M.

CHEMISTRYSELECT , cilt.11, sa.11, 2026 (SCI-Expanded, Scopus)

5. Novel triphenylphosphonium-hydrazone salts: ıntegrated experimental and computational ınsights into AChE ınhibition and resistance-overcoming antimicrobial and antibiofilm potential

Yıldırım M., Ünver H., Necip A., Hord B., ERŞATIR M.

Naunyn-Schmiedeberg's Archives of Pharmacology , cilt.399, sa.6, ss.9189-9201, 2026 (SCI-Expanded, Scopus)

6. Green Fabrication of Copper and Zinc Nanoflowers Using Rheum tataricum L. and Evaluation of their Antioxidant, Enzyme-Inhibitory, Antimicrobial, and Anticancer Properties

Yıldırım M., Yilmaz B. S., Çimentepe M., Necip A., Dellal Ö.

Cell Biochemistry and Biophysics , cilt.84, sa.1, ss.1475-1487, 2026 (SCI-Expanded, Scopus)

7. Synthesis, Characterization, and Biological Evaluation of Quercetin-Boronate@Cu-hNFs and Quercetin-Boronate@Zn-hNFs: AChE Inhibition, Antioxidant, Anticancer, Antibacterial, Antibiofilm Activity Against Multidrug-Resistant Bacteria and Molecular Docking Studies

Yıldırım M., Yilmaz B. S., Çimentepe M., Necip A., ÖZTÜRK G., Kiliç A.

Journal of Inorganic and Organometallic Polymers and Materials , cilt.36, sa.4, ss.2319-2333, 2026 (SCI-Expanded, Scopus)

8. Supercritical CO2 Extracts of Onosma Decorticans Riedl: Phytochemical Profiling and Antioxidant, Antibacterial, and Anticancer Activities

Yıldırım M., Binzet G., Binzet R., Yabalak E.

ChemistrySelect , cilt.11, sa.8, 2026 (SCI-Expanded, Scopus)

9. Antioxidant, anti-acetylcholinesterase, antimicrobial, and anticancer activities of Morin–Cu(II) hybrid Nanoflowers

Yıldırım M., Yilmaz B. S., Çimentepe M., Necip A., Dellal Ö.

Polyhedron , cilt.285, 2026 (SCI-Expanded, Scopus)

10. Recent advances in bacterial cellulose: From sustainable production to environmental, biomedical, and 3D bioprinting applications

Yildirim M., Ermis E., Amangeldinova M., Yabalak E.

CHEMICAL ENGINEERING RESEARCH & DESIGN , cilt.226, ss.515-535, 2026 (SCI-Expanded, Scopus)

11. Multifunctional Bioactivities of Ellagic Acid-Based Hybrid Cu, Zn, and Co Microflowers: Antioxidant, Anti-AChE, Anticancer, and Antibacterial Effects

Yıldırım M., Yilmaz B. S., Çimentepe M., Necip A., ÖZTÜRK G.

Journal of Cluster Science , cilt.37, sa.1, 2026 (SCI-Expanded, Scopus)

12. **Eco-Friendly Synthesis of Copper Nanoflowers Using Rheum Cordatum Losinsk Leaf Extracts for Photocatalytic Dye Degradation and Biomedical Applications**

Yildirim M., Yilmaz B., Çimentepe M., Necip A., Asfoor A., Hord B.

CELL BIOCHEMISTRY AND BIOPHYSICS , 2026 (SCI-Expanded, Scopus)

13. **Morin-functionalized pHEMA cryogel membranes for combating MDR Escherichia coli and MRSA: antibacterial efficacy and molecular docking study**

Cimentepe Ö., Cimentepe M., Dogan K., Yildirim M.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , 2026 (SCI-Expanded, Scopus)

14. Novel benzimidazole based cobalt complex: synthesis, AChE enzyme inhibition, antibacterial and antibiofilm activity against multidrug-resistant bacteria, and computational analysis

Çimentepe M., Ünver H., Necip A., Yıldırım M.

Polyhedron , cilt.283, 2026 (SCI-Expanded, Scopus)

15. Boron-ellagic acid hybrids as a molecular arrow: multi-targeted inhibition of AChE, anticancer activity, and antimicrobial action against MRSA and MDR E. coli, supported by docking analyses

Yildirim M., Yasar E., Necip A., Cimentepe M., ÖZTÜRK G., Kilic A.

Journal of Molecular Liquids , cilt.440, 2025 (SCI-Expanded, Scopus)

16. Synthesis and Biological Evaluation of P, N-Type Schiff Bases, Secondary Amines, and Thioamide Derivatives with Molecular Docking Studies

Akgul I., Dogan M., Cevik P. K., Yildirim M., Yilmaz O.

Chemistry and Biodiversity , cilt.22, sa.12, 2025 (SCI-Expanded, Scopus)

17. Microplastics in the human body and environment: Pathways, health impacts, detection, and removal strategies

Aminzai M., Yildirim M., Yabalak E.

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING , cilt.13, sa.6, 2025 (SCI-Expanded, Scopus)

18. Multifunctional benzimidazolium derivatives as anticancer, antibacterial, and acetylcholinesterase inhibitors: In vitro and molecular docking studies

Yıldırım M., Ünver H., Necip A., Çimentepe M., ERŞATIR M.

Archives of Biochemistry and Biophysics , cilt.774, 2025 (SCI-Expanded, Scopus)

19. Unveiling the Multifaceted Bioactivities of Benzimidazolium Salts: Synthesis, Characterization, and Computational Insights Into AChE Inhibition and Antimicrobial Action Against Multidrug Resistance Bacteria MRSA and MDR E. coli

Yıldırım M., Ünver H., Necip A., Çimentepe M., ERŞATIR M.

ChemistrySelect , cilt.10, sa.43, 2025 (SCI-Expanded, Scopus)

20. “One stone, two birds” strategy: quercetin-boronate-loaded pHEMA cryogel membranes for targeted action against methicillin-resistant Staphylococcus aureus and multidrug-resistant Escherichia coli with molecular docking insights

Yildirim M., Cimentepe M., Yarlılar Ş. G., Kilic A.

Colloid and Polymer Science , cilt.303, sa.11, ss.2319-2330, 2025 (SCI-Expanded, Scopus)

21. Harnessing marine plant extracts for sustainable agriculture, livestock management, industrial use, and biomedical applications

Yildirim M., Amangeldinova M., Poyraz S., Erşatır M., Mussayeva A., Kudrina N.

FRONTIERS IN PLANT SCIENCE , cilt.16, sa.1686511., 2025 (SCI-Expanded, Scopus)

22. Next-generation antibacterial cryogels: Berberine-infused smart membranes with molecular docking-guided targeting of MRSA and MDR E. coli

Yildirim M., Cimentepe M., Dogan K., Necip A., Amangeldinova M.

Biophysical Chemistry , cilt.325, 2025 (SCI-Expanded, Scopus)

23. Novel vanillin-derived Schiff Bases: Synthesis, characterization, antibacterial activity, enzyme inhibition, antioxidant activity, anti-inflammatory activity on LPS-induced RAW264.7 macrophage cell line, and In Silico studies

Demirbağ B., Yildirim M., Cimentepe M., Necip A., Unver H., Tiftik E. N.

Journal of Molecular Structure , cilt.1338, 2025 (SCI-Expanded, Scopus)

24. Design, synthesis, and biological evaluation of novel vanillin-derived hydrazone compounds with antimicrobial, anticancer, and enzyme inhibition activities, along with molecular structure and drug-likeness assessment

Yıldırım M., Ünver H., Necip A., Çimentepe M.

Biochemical and Biophysical Research Communications , cilt.775, 2025 (SCI-Expanded, Scopus)

25. Tea Tree Oil-Loaded Chitosan Hydrogels for Enhanced Wound Healing and Antimicrobial Activity

Yildirim M., Dogan K., Yigin A., Cimentepe M., Necip A., Amangeldinova M., et al.

CHEMISTRYSELECT , cilt.10, sa.30, 2025 (SCI-Expanded, Scopus)

26. A breakthrough in infection control: niaouli oil–chitosan hydrogels for enhanced wound healing

Yildirim M., Dogan K., Yiğin A., Cimentepe M., Necip A., Amangeldinova M., et al.

Polymer Bulletin , cilt.82, sa.12, ss.7265-7288, 2025 (SCI-Expanded, Scopus)

27. **TRP Channel Inhibition and NF-κB Pathway Suppression in Human Ependymal Tumor cell-line by Achillea Biebersteinii Aqueous Extract**

Özbay E., Çömelekoglu U., Sögüt F., Yildirim M., Küççüktürk S., Duran T., et al.

CELL BIOCHEMISTRY AND BIOPHYSICS , 2025 (SCI-Expanded, Scopus)

28. **Bioactive Potential of Rheum cordatum Losinsk. Leaf Extracts: Phytochemical Insights from Supercritical CO₂, Subcritical Ethanol and Ultrasound-Assisted Extractions**

Amangeldinova M., Ersatir M., Cevik P., Yilmaz M., Cakir O., Kudrina N., et al.

PLANTS-BASEL , cilt.14, sa.15, 2025 (SCI-Expanded, Scopus)

29. Liposome-Encapsulated Antibiotics for the Therapy of Mycobacterial Infections

Yildirim M., Düzgünes N.

ANTIBIOTICS-BASEL , cilt.14, sa.7, 2025 (SCI-Expanded, Scopus)

30. Boron Compounds as Key Drivers of Innovation: Exploring Their Role in Environmental Remediation, Sustainable Agriculture, Advanced Biomedical Applications, and Green Chemistry

Yildirim M., ERŞATIR M., Saleh M., Demirbağ B., Yabalak E., Kilic A.

Journal of Organometallic Chemistry , cilt.1035, 2025 (SCI-Expanded, Scopus)

31. Salicylaldehyde-derived Hydrazones: Synthesis, characterization, antibacterial activity, antioxidant and anti-inflammatory effects on LPS-induced RAW264.7 macrophage cells, drug-likeness properties, and molecular docking analysis

Demirbağ B., Yıldırım M., Çimentepe M., Necip A., Ünver H., Tiftik E. N.

Biochemical and Biophysical Research Communications , cilt.766, 2025 (SCI-Expanded, Scopus)

32. Chitosan hydrogels: Versatile platforms for drug delivery in cancer treatment, wound dressing, and 3D bioprinting applications

Yildirim M., Poyraz S., Acet Ö., Acet B., Karakoç V., Odabasi M.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , cilt.314, 2025 (SCI-Expanded, Scopus)

33. Green Extraction Strategies and Bioactivity of Rheum cordatum Losinsk: Antioxidant, Antimicrobial, and Molecular Docking Insights

Amangeldinova M., ERŞATIR M., Necip A., Cimentepe M., Kudrina N., Terletskaya N., et al.

Plants , cilt.14, sa.7, 2025 (SCI-Expanded, Scopus)

34. Facile synthesis and spectral analysis of the bioactive spiroborate compounds as a novel therapeutic agent for computational insights, biological evaluation, and applications

Yildirim M., Yasar E., Necip A., Cimentepe M., Demirbağ B., Kilic A.

Journal of Organometallic Chemistry , cilt.1027, 2025 (SCI-Expanded, Scopus)

35. Synthesis of bioactive quercetin-boronate esters as a novel biological agent: Enzyme inhibition, anti-microbial properties, computational insights and anti-cancer activity

Yildirim M., Kilic A., Cimentepe M., Necip A., Turedi S.

Journal of Molecular Structure , cilt.1321, 2025 (SCI-Expanded, Scopus)

36. Naringenin-loaded pHEMA cryogel membrane: preparation, characterization, antibacterial activity and in silico studies

Yildirim M., Dogan K., Necip A., Cimentepe M.

CHEMICAL PAPERS , cilt.79, sa.1, ss.211-220, 2025 (SCI-Expanded, Scopus)

37. Phytochemical profiling and evaluation of antioxidant, antimicrobial, and cytotoxic activities of endemic Onosma angustissima

Binzet G., Yıldırım M., Binzet R., Yabalak E.

International Journal of Environmental Health Research , 2025 (SCI-Expanded, Scopus)

38. Innovative Nanoformulation Strategies of Hesperetin and Hesperidin: Pioneering Advances in Pharmaceutical Applications (A Review)

Poyraz S., Cimentepe M., Cimentepe O., Yildirim M.

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY , cilt.50, sa.6, ss.2397-2425, 2024 (SCI-Expanded, Scopus)

39. Investigation of the anticancer effect of newly synthesized palladium conjugate Schiff base metal complexes on non-small cell lung cancer cell line and mouse embryonic fibroblast cell line

Demirbağ B., Büyükafşar K., Kaya H., Yıldırım M., Bucak Ö., Ünver H., et al.

Biochemical and Biophysical Research Communications , cilt.735, 2024 (SCI-Expanded, Scopus)

40. Innovative approach against cancer: Thymoquinone-loaded PHEMA-based magnetic nanoparticles and their effects on MCF-7 breast cancer

Yıldırım M., Acet Ö., Önal Acet B., Karakoç V., Odabaşı M.

Biochemical and Biophysical Research Communications , cilt.734, 2024 (SCI-Expanded, Scopus)

41. Things to Know and Latest Trends in the Design and Application of Nanoplatforms in Cancer Treatment

Yildirim M., Acet B., Dikici E., Odabasi M., Acet Ö.

BIONANOSCIENCE , cilt.14, sa.4, ss.4167-4188, 2024 (ESCI, Scopus)

42. **Thymoquinone-Loaded pHEMA Cryogel Membranes for Superior Control of Staphylococcus aureus Infections**

Yildirim M., Cimentepe M., Dogan K., Necip A., Amangeldinova M., Dellal Ö., et al.

RUSSIAN JOURNAL OF GENERAL CHEMISTRY , cilt.94, sa.11, ss.3079-3089, 2024 (SCI-Expanded, Scopus)

43. Enhanced Anti-Cancer Efficacy of Hesperidin through Smart Polymeric Nanoparticles Targeting Prostate Cancer

Yildirim M., Acet O., Acet B., Karakoç V., Odabasi M.

CHEMISTRYSELECT , cilt.9, sa.36, 2024 (SCI-Expanded, Scopus)

44. Investigation of the anticancer of photodynamic therapy effects by using the novel Schiff base ligand palladium complexes on human breast cancer cell line

Demirbag B., Balli E., Yildirim M., Ünver H., Temel G., Yilmaz M., et al.

CHEMICAL PAPERS , cilt.78, sa.13, ss.7611-7621, 2024 (SCI-Expanded, Scopus)

45. Green Extraction of Plant Materials Using Supercritical CO2: Insights into Methods, Analysis, and Bioactivity

Yıldırım M., ERŞATIR M., Poyraz S., Amangeldinova M., Kudrina N. O., Terletskaya N. V.

Plants , cilt.13, sa.16, 2024 (SCI-Expanded, Scopus)

46. Recent pharmacological insights about imidazole hybrids: a comprehensive review

Poyraz S., Yıldırım M., ERŞATIR M.

Medicinal Chemistry Research , cilt.33, sa.6, ss.839-868, 2024 (SCI-Expanded, Scopus)

47. Tetrahedral Boronate Ester as Regulators of Inflammation and Adhesion in ox-LDL Induced Atherosclerotic Model

Degirmenci U., Kilic A., Söylemez R., Yildirim M.

Russian Journal of Bioorganic Chemistry , cilt.50, sa.1, ss.106-115, 2024 (SCI-Expanded, Scopus)

48. Potential Protective Effects of Ruta Chalepensis L. Extracts Against Gentamicin-Induced Nephrotoxicity via Reduction on Apoptotic, DNA Damage and Oxidative Stress Markers in Mice

Yildirim M., ERŞATIR M., Degirmenci U., Yigin A., Unal M. B., Guldur M. E., et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH , cilt.33, sa.12, ss.1533-1545, 2023 (SCI-Expanded, Scopus)

49. Immunomodulatory activities of pH/temperature sensitive smart naringenin-loaded nanopolymers on the mammalian macrophages

Yildirim M., Acet Ö.

Applied Surface Science Advances , cilt.18, 2023 (ESCI, Scopus)

50. Protective effect of paricalcitol in rat testicular damage induced by subchronic 1800 MHz radiofrequency radiation

Demirbağ B., Aktaş S., Çömelekoğlu Ü., Kara İ., Yildirim M., Yildirim D. D.

Biochemical and Biophysical Research Communications , cilt.680, ss.42-50, 2023 (SCI-Expanded, Scopus)

51. Recent Strategies for Cancer Therapy: Polymer Nanoparticles Carrying Medicinally Important Phytochemicals and Their Cellular Targets

Yildirim M., Sessevmez M., Poyraz S., Düzgünes N.

PHARMACEUTICS , cilt.15, sa.11, 2023 (SCI-Expanded, Scopus)

52. The Effect of Elasticity of Gelatin Nanoparticles on the Interaction with Macrophages

Yildirim M., Weiss A., Schneider M.

Pharmaceutics , cilt.15, sa.1, 2023 (SCI-Expanded, Scopus)

53. Anti-cancer activity of naringenin loaded smart polymeric nanoparticles in breast cancer

Yıldırım M., Acet Ö., Yetkin D., Acet B. Ö., Karakoc V., Odabası M.

Journal of Drug Delivery Science and Technology , cilt.74, 2022 (SCI-Expanded, Scopus)

54. Bacteriophage therapy of bacterial infections: The rediscovered frontier

Düzgüneş N., SESSEVMEZ M., Yildirim M.

Pharmaceuticals , cilt.14, sa.1, ss.1-16, 2021 (SCI-Expanded, Scopus)

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