Green Extraction of Plant Materials Using Supercritical CO2: Insights into Methods, Analysis, and Bioactivity


Yıldırım M., ERŞATIR M., Poyraz S., Amangeldinova M., Kudrina N. O., Terletskaya N. V.

Plants, vol.13, no.16, 2024 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 13 Issue: 16
  • Publication Date: 2024
  • Doi Number: 10.3390/plants13162295
  • Journal Name: Plants
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, Food Science & Technology Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Keywords: anticancer activity, extraction, green chemistry, medicinal plants, supercritical carbon dioxide, supercritical fluid
  • Çukurova University Affiliated: Yes

Abstract

In recent years, the supercritical CO2 extraction method has gained attention due to its use of environmentally friendly, non-toxic solvents, ability to operate at lower temperatures that do not cause the degradation of bioactive compounds, and capacity for rapid extraction. This method is particularly notable for isolating bioactive compounds from plants. The extracts obtained have shown superior properties due to their activity against diseases such as cancer, which is one of the leading causes of death worldwide. The aim of this study is to provide an in-depth understanding of the supercritical CO2 extraction method, as well as to discuss its advantages and disadvantages. Furthermore, the study includes specific data on various plant materials, detailing the following parameters: plant name and region, bioactive compounds or compound classes, extraction temperature (°C), pressure (bar), time (minutes), co-solvent used, and flow rate. Additionally, this study covers extensive research on the isolation of bioactive compounds and the efficacy of the obtained extracts against cancer.