Doç. Dr. CEM YAMALI

Yayın Ağı

Makaleler 47

1. Non-invasive detection of protein aggregation in biopharmaceuticals using TD-NMR and MRI

Ozesme Taylan G., Alam H., Mercan E., Erkan E., YAMALI C., ÖZTOP H. M.

European Journal of Pharmaceutics and Biopharmaceutics , cilt.215, 2025 (SCI-Expanded)

2. Synthesis, Bioactivities, and in Silico Studies of Novel Benzo[d][1,3]Dioxole-Based Pyrazoline Sulfonamides

Tugrak Sakarya M., GÜL H. İ., YAMALI C., Sakagami H., Saglamtas R., SERT Y., et al.

Polycyclic Aromatic Compounds , 2025 (SCI-Expanded)

3. Synergistic quantification of mixed insulin preparations using time domain NMR techniques

Alam H., Ozesme Taylan G., YAMALI C., ÖZTOP H. M.

Journal of Pharmaceutical and Biomedical Analysis , cilt.247, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

4. Pharmaceutical Studies on Piperazine-Based Compounds Targeting Serotonin Receptors and Serotonin Reuptake Transporters.

Yamali C., Nenni M., Sakarya M. T., Kaplan H. A.

Mini reviews in medicinal chemistry , 2024 (SCI-Expanded)

5. In Vitro Enzyme Activity and Molecular Docking Studies of Pyrazoline Derivatives as Monoamine Oxidase Inhibitors

Sakarya M. T., GÜL H. İ., YAMALI C., ÖZKAY Y., Tok T. T.

Pharmaceutical Chemistry Journal , cilt.58, sa.3, ss.419-427, 2024 (SCI-Expanded)

6. Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and antimicrobial agents.

Poyraz S., Dondas H. A., Yamali C., Belveren S., Demir Y., Aydinoglu S., et al.

Journal of biomolecular structure & dynamics , cilt.42, sa.7, ss.3441-3458, 2024 (SCI-Expanded)

7. Biological Activities and Drug-Likeness Properties of Phenol-Based Heterocyclic Compounds

YAMALI C., NENNİ M., Sakarya M. T., Sakagami H., GÜL H. İ.

Pharmaceutical Chemistry Journal , 2024 (SCI-Expanded)

8. Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design.

Yamali C., Gul M., Gul H. I.

Current topics in medicinal chemistry , 2023 (SCI-Expanded)

9. IMIDAZOLINONE-BASED SULFONAMIDE DERIVATIVES: SYNTHESIS, CHARACTERIZATION, AND INHIBITORY PROPERTY AGAINST SOME METABOLIC ENZYMES

Tuğrak Sakarya M., Gul H. I., Yamali C., Demir Y., Gulcin i.

Ankara Üniversitesi Eczacılık Fakültesi Dergisi , cilt.47, sa.3, ss.915-926, 2023 (Scopus)

10. Design, synthesis, and assessment of pharmacological properties of indole-based fluorinated chalcones and their benzenesulfonamide analogs

Yamalı C., Sevin S., Nenni M., Tugrak Sakarya M., Uyar R., Aygul A., et al.

CHEMICAL PAPERS , cilt.77, sa.12, ss.7903-7918, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

11. Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and antimicrobial agents

Poyraz S., Döndaş H. A., Yamalı C., Belveren S., Demir Y., Aydınoğlu S., et al.

JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS , sa.1, ss.1-18, 2023 (SCI-Expanded)

12. Molecular docking studies and biological activities of benzenesulfonamide-based thiourea and thiazolidinone derivatives targeting cholinesterases, α-glucosidase, and α-amylase enzymes

TUĞRAK SAKARYA M., GÜL H. İ., YAMALI C., TASLIMI P., TAŞKIN TOK T.

The Turkish Chemical Society , cilt.10, sa.2, ss.385-424, 2023 (Hakemli Dergi)

13. Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease

Yamalı C., Donmez S.

MINI-REVIEWS IN MEDICINAL CHEMISTRY , cilt.1, sa.1, ss.1, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

14. N-Benzoylthiourea-pyrrolidine carboxylic acid derivatives bearing an imidazole moiety: Synthesis, characterization, crystal structure, in vitro ChEs inhibition, and antituberculosis, antibacterial, antifungal studies

POYRAZ S., DÖNDAŞ H. A., Sansano J., Belveren S., YAMALI C., Ülger M., et al.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1273, ss.134303, 2023 (SCI-Expanded)

15. Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores.

Yamali C., Sakagami H., Satoh K., Bandow K., Uesawa Y., Bua S., et al.

Bioorganic chemistry , cilt.127, ss.105969, 2022 (SCI-Expanded)

16. Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies

Yamali C., Gul H. I., Tugrak Sakarya M., Nurpelin Saglik B., Ece A., Demirel G., et al.

BIOORGANIC CHEMISTRY , cilt.124, 2022 (SCI-Expanded)

17. Effects of a Novel Benzenesulfonamide 4-(3-(4-Bromophenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) on Antioxidant Enzymes and Hematological Parameters of Rainbow Trout (Oncorhynchus mykiss)

Ozgun D. O., ALAK G., UÇAR A., Bilginer S., GÜL H. İ., Kocaman M., et al.

PAKISTAN JOURNAL OF ZOOLOGY , cilt.53, sa.6, ss.2083-2089, 2021 (SCI-Expanded)

18. Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides.

Yamali C., Inci Gul H., Ozli G., Angeli A., Ballar Kirmizibayrak P., Erbaykent Tepedelen B., et al.

Bioorganic chemistry , cilt.115, ss.105194, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

19. Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.

Yamali C., Sakagami H., Uesawa Y., Kurosaki K., Satoh K., Masuda Y., et al.

European journal of medicinal chemistry , cilt.217, ss.113351, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

20. Inhibitory effects of novel benzamide derivatives towards acetylcholinesterase enzyme

YAMALI C., GÜL H. İ., LEVENT S., DEMİR Y.

Journal of the Turkish Chemical Society Section A: Chemistry , cilt.8, sa.2, ss.429-434, 2021 (Scopus)

21. Biological activities of a newly synthesized pyrazoline derivative 4-(3-(4-bromophenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide (B4) compound on rainbow trout alevins, Oncorhynchus mykiss.

Ucar A., Ozmen Ozgun D., Alak G., Gul H. I., Kocaman M., Yamalı C., et al.

In vitro cellular & developmental biology. Animal , cilt.57, ss.17-20, 2021 (SCI-Expanded)

22. Phenothiazine-based chalcones as potential dual-target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO-A, MAO-B)

Yamali C., Engin F. S., Bilginer S., Tuğrak M., Ozmen Ozgun D., Özli G., et al.

JOURNAL OF HETEROCYCLIC CHEMISTRY , cilt.58, sa.1, ss.161-171, 2021 (SCI-Expanded)

23. Inhibitory effects of the chalcones towards carbonic anhydrase I, II andacetylcholinesterase enzymes

TUĞRAK M., YAMALI C., GÜL H. İ., DEMİR Y.

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi , cilt.13, sa.3, ss.1138-1146, 2020 (Hakemli Dergi)

24. Cytotoxic effects of Mannich bases via induction of caspase-3 pathway on human oral squamous cell carcinoma

YAMALI C., GÜL H. İ.

Journal of the Turkish Chemical Society Section A: Chemistry , cilt.8, sa.1, ss.187-194, 2020 (Scopus)

25. Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes

Yamali C., Gül H. İ., Kazaz C., Levent S., Gülçin İ.

BIOORGANIC CHEMISTRY , cilt.96, 2020 (SCI-Expanded)

26. Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors

YAMALI C., GÜL H. İ., Çakır T., Demir Y., GÜLÇİN İ.

LETTERS IN DRUG DESIGN & DISCOVERY , cilt.17, sa.10, ss.1283-1292, 2020 (SCI-Expanded)

27. Synthesis and bioactivities of 1-(4-hydroxyphenyl)-2-((heteroaryl)thio)ethanones as carbonic anhydrase I, II and acetylcholinesterase inhibitors

Yamali C., GÜL H. İ., Demir Y., KAZAZ C., GÜLÇİN İ.

TURKISH JOURNAL OF CHEMISTRY , cilt.44, sa.4, ss.1058-1067, 2020 (SCI-Expanded)

28. Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors

Yamali C., GÜL H. İ., Ece A., Bua S., Angeli A., Sakagami H., et al.

BIOORGANIC CHEMISTRY , cilt.92, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

29. Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

Ozgun D. O., GÜL H. İ., Yamali C., Sakagami H., GÜLÇİN İ., Sukuroglu M., et al.

BIOORGANIC CHEMISTRY , cilt.84, ss.511-517, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

30. Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates

GÜL H. İ., Yamali C., Gunesacar G., Sakagami H., Okudaira N., Uesawa Y., et al.

MEDICINAL CHEMISTRY RESEARCH , cilt.27, sa.10, ss.2366-2378, 2018 (SCI-Expanded)

31. Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes

Gül H. İ., Yamali C., Bulbuller M., Kirmizibayrak P. B., Gül M., Angeli A., et al.

BIOORGANIC CHEMISTRY , cilt.78, ss.290-297, 2018 (SCI-Expanded)

32. Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells

Badr G., GÜL H. İ., Yamali C., Mohamed A. A. M., Badr B. M., GÜL M., et al.

BIOORGANIC CHEMISTRY , cilt.78, ss.46-57, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

33. Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes

Yamali C., GÜL H. İ., Ece A., Taslimi P., GÜLÇİN İ.

CHEMICAL BIOLOGY & DRUG DESIGN , cilt.91, sa.4, ss.854-866, 2018 (SCI-Expanded)

34. New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors

GÜL H. İ., Yamali C., Sakagami H., Angeli A., Leitans J., Kazaks A., et al.

BIOORGANIC CHEMISTRY , cilt.77, ss.411-419, 2018 (SCI-Expanded)

35. Microwave-assisted synthesis and bioevaluation of new sulfonamides.

Gul H. I., Yamali C., Yesilyurt F., Sakagami H., Kucukoglu K., Gulcin I., et al.

Journal of enzyme inhibition and medicinal chemistry , cilt.32, ss.369-374, 2017 (SCI-Expanded)

36. Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents

Yamali C., Ozgun D. O., GÜL H. İ., Sakagami H., KAZAZ C., Okudaira N.

MEDICINAL CHEMISTRY RESEARCH , cilt.26, sa.9, ss.2015-2023, 2017 (SCI-Expanded)

37. Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl] benzenesulfonamides

GÜL H. İ., METE E., Eren S. E., Sakagami H., Yamali C., Supuran C. T.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.32, sa.1, ss.169-175, 2017 (SCI-Expanded)

38. Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones

Yamali C., GÜL H. İ., Ozgun D. O., Sakagami H., Umemura N., KAZAZ C., et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , cilt.17, sa.10, ss.1426-1433, 2017 (SCI-Expanded)

39. Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines

Kucukoglu K., Oral F., Aydin T., Yamali C., Algul O., Sakagami H., et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, ss.20-24, 2016 (SCI-Expanded)

40. Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase

Ozgun D. O., Yamali C., GÜL H. İ., Taslimi P., GÜLÇİN İ., YANIK T., et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.6, ss.1498-1501, 2016 (SCI-Expanded)

41. Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases

Yamali C., GÜL H. İ., Sakagami H., Supuran C. T.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, ss.125-131, 2016 (SCI-Expanded)

42. Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2,3-dihydroinden-1-one and evaluation of their cytotoxicities

TUĞRAK M., Yamali C., Sakagami H., GÜL H. İ.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.5, ss.818-823, 2016 (SCI-Expanded)

43. The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes

Yamali C., TUĞRAK M., GÜL H. İ., Tanc M., Supuran C. T.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.6, ss.1678-1681, 2016 (SCI-Expanded)

44. Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

GÜL H. İ., Yamali C., Yasa A. T., Unluer E., Sakagami H., Tanc M., et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.6, ss.1375-1380, 2016 (SCI-Expanded)

45. Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects

GÜL H. İ., Kucukoglu K., Yamali C., BİLGİNER S., YUCA H., Ozturk I., et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.4, ss.568-573, 2016 (SCI-Expanded)

46. Synthesis of some 3(2H)-pyridazinone and 1(2H)-phthalazinone derivatives incorporating aminothiazole moiety and investigation of their antioxidant, acetylcholinesterase, and butyrylcholinesterase inhibitory activities

Yamali C., Gulcan H. O., Kahya B., Cobanoglu S., Sukuroglu M. K., Dogruer D. S.

MEDICINAL CHEMISTRY RESEARCH , cilt.24, sa.3, ss.1210-1217, 2015 (SCI-Expanded)

47. Synthesis of Some New 3(2H)-Pyridazinone Derivatives and Evaluation of their Analgesic-anti-inflammatory and Antimicrobial Activities

Sukuroglu M., Yamali C., Tiryaki D., Onurdag F. K., Akkol E., Dogruer D. S.

LETTERS IN DRUG DESIGN & DISCOVERY , cilt.10, sa.6, ss.507-514, 2013 (SCI-Expanded)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 27

1. Monoamine oxidase inhibition and toxicity evaluation of phenylurea-bearing hydrazones

YAMALI C., DEMİREL G.

6th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2023) October 11-13, 2023., Ankara, Türkiye, 11 - 13 Ekim 2023, (Özet Bildiri)

2. A PRELIMINARY STUDY OF CHOLINESTERASE INHIBITION AND CYTOTOXICITY EVALUATION OF INDOLEBASED CHALCONE DERIVATIVE

YAMALI C., DEMİREL G.

International Multidisciplinary Symposium on Drug Research and Development DRD 2023, İzmir, Türkiye, 4 - 06 Mayıs 2023, (Özet Bildiri)

3. Paraoxonase Enzyme Inhibition Effects Of Sulfonamide Bearing Compounds

DEDEOĞLU N., YAMALI C.

5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022) November 23-25, 2022., Türkiye, 23 Kasım 2022, (Özet Bildiri)

4. The design of modern tacrine-based drug candidates in the treatment of Alzheimer's disease

Dönmez Ş., YAMALI C.

5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022) November 23-25, 2022, Türkiye, 23 Kasım 2022, (Özet Bildiri)

5. The Effects of Some Secondary Sulfonamide Derivatives on Lactoperoxidase Enzyme Activity

DEDEOĞLU N., YAMALI C.

6th INTERNATIONAL CONGRESS on APPLIED BIOLOGICAL SCIENCE, Türkiye, 8 - 09 Aralık 2021, ss.33-38, (Tam Metin Bildiri)

6. Pirazol-Benzensülfonamit Grubu Taşıyan Schiff Bazı Türevinin Sentezi ve Karbonik Anhidraz Enzimleri Üzerine Etkisi

YAMALI C.

32. Ulusal Kimya Kongresi, Türkiye, 17 - 19 Eylül 2020, (Özet Bildiri)

7. THE ROLE OF CARBONIC ANHYDRASE ENZYMES INANTICANCER DRUG RESEARCH

YAMALI C.

EURO ASIA 7th. INTERNATIONAL CONGRESS ON APPLIED SCIENCES, 21 - 22 Ağustos 2020, (Özet Bildiri)

8. Synthesis of novel (E)-1-(4-hydroxy-3-((4-phenylpiperazin-1-yl)methyl)phenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one as a selective cytotoxic agent.

YAMALI C.

INSAC - Natural and Health Sciences Congress 2020, 22 - 23 Mayıs 2020, (Özet Bildiri)

9. Synthesis of potential bioactive pyrazole-carboxamides

YAMALI C., GÜL H. İ.

3rd International Eurasian Conference on Biological and Chemical Sciences(EurasianBioChem 2020)March 19-20, 2020 / Ankara, Turkey, 19 - 20 Mart 2020, (Özet Bildiri)

10. -1-(4-Sülfamoilfenil)-5-(tiyofen-2-il)-1H-pirazol-3-(N-sübstitüe) karboksamitlerin sentezi ve kimyasal yapılarının aydınlatılması

YAMALI C., ÖZLİ G., GÜL H. İ.

3rd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2020), March 19-20, 2020 Ankara, Turkey, 19 - 20 Mart 2020, (Özet Bildiri)

11. Pyrazole-Benzensulfonamides: Inhibitory Effects On Cancer-Associated Carbonic Anhydrase IX (CA IX) Isoenzyme

YAMALI C., GÜL H. İ., Supuran C. T.

ISPEC- 5 th INTERNATIONAL CONFERENCE ON ENGINEERING NATURAL SCIENCES, 20 - 22 Aralık 2019, (Özet Bildiri) Sürdürülebilir Kalkınma

12. Inhibitory Effects of Isatin Mannich Bases on Carbonic Anhydrases, Acetylcholinesterase,and Butyrylcholinesterase

ÖZMEN ÖZGÜN D., YAMALI C., GÜL H. İ., TASLİMİ P., GÜLÇİN İ., YANIK T., et al.

2018 5th International Conference on Chemical and Biological Sciences (ICCBS 2018) BUCHAREST CONFERENCE, ROMANIA, Romanya, 7 - 09 Mart 2018, (Özet Bildiri)

13. Structure Elucidation Of 1-(2,5/3,5-difluorophenyl)-3 (2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones

KAZAZ C., GÜL H. İ., YAMALI C.

The International Workshop on the Application of NMR in Pharmaceutics, Phytotherapeutics and Medicine, Bezmialem Vakıf Üniversitesi, İstanbul, Turkey, İstanbul, Türkiye, 15 - 17 Kasım 2017, (Özet Bildiri)

14. Bioactivities of Isatin Mannich Bases

ÖZMEN ÖZGÜN D., GÜL H. İ., YAMALI C.

3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, 5 - 07 Ekim 2017, (Özet Bildiri)

15. 1,5-Bis(4-hydroxy-3-(aminomethyl)phenyl)penta-1,4-dien-3-ones: Bis Mannich Bases as Anticancer Agents

GÜL H. İ., YAMALI C., Sakagami H.

3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, Erzurum, Türkiye, 5 - 07 Ekim 2017, (Özet Bildiri)