Copy For Citation
Yamali C., GÜL H. İ., Ozgun D. O., Sakagami H., Umemura N., KAZAZ C., ...More
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.17, no.10, pp.1426-1433, 2017 (SCI-Expanded)
-
Publication Type:
Article / Article
-
Volume:
17
Issue:
10
-
Publication Date:
2017
-
Doi Number:
10.2174/1871520617666170327123909
-
Journal Name:
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
-
Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
-
Page Numbers:
pp.1426-1433
-
Keywords:
Chalcone, cytotoxicity, dimethoxy, difluoro, potency selectivity expression, dental cells, PARP, MOLECULAR TARGET PERSPECTIVES, MANNICH BASE DERIVATIVES, CARBONIC-ANHYDRASE I, CANCER CELLS, INHIBITORS, ACETYLCHOLINESTERASE, APOPTOSIS
-
Çukurova University Affiliated:
No
Abstract
Background: Although anticancer chemotherapeutics are available in markets, side effects related to the drugs in clinical use lead to researchers to investigate new drug candidates which are more safe, potent and selective than others. Chalcones are popular with their anticancer activities with the several reported mechanisms including inhibition of angiogenesis, inhibition of tubulin polymerization, and induction of apoptosis etc.