Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones


Yamali C. , GÜL H. İ. , Ozgun D. O. , Sakagami H., Umemura N., KAZAZ C., ...Daha Fazla

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.17, ss.1426-1433, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 17 Konu: 10
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1871520617666170327123909
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Sayfa Sayıları: ss.1426-1433

Özet

Background: Although anticancer chemotherapeutics are available in markets, side effects related to the drugs in clinical use lead to researchers to investigate new drug candidates which are more safe, potent and selective than others. Chalcones are popular with their anticancer activities with the several reported mechanisms including inhibition of angiogenesis, inhibition of tubulin polymerization, and induction of apoptosis etc.