Announcements & Documents
HETEROSİKLİK KİMYA
Lecture Note
5/27/2022
BU DERS SUNUMU HETEROSİKLİK BİLEŞİKLERİN SENTEZİ, TEPKİMELERİ VE DİĞER KİMYASAL ÖZELLİKLERİ İLE İLGİLİ GENEL BİLGİLERİ İÇERMEKTEDİR.
Education Information
2013 - 2018
2013 - 2018Doctorate
Ataturk University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri, Turkey
2009 - 2011
2009 - 2011Postgraduate
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri, Turkey
2005 - 2009
2005 - 2009Undergraduate
Kirikkale University, Faculty Of Arts And Scıences, Department Of Chemıstry, Turkey
Dissertations
2018
2018Doctorate
Pirazol-benzensülfonamit türevi bileşiklerin tasarımı, sentezi, kimyasal yapılarının aydınlatılması ve biyoaktiviteleri
Ataturk University, Sağlık Bilimleri Enstitüsü, Eczacılık Farmasötik Kimya Anabilim Dalı Başkanlığı
2011
2011Postgraduate
Bazı 3(2H)-Piridazinon ve 1(2H)-Fitalazinon türevlerinin sentezi ve biyolojik etkilerinin incelenmesi
Gazi University
Certificates, Courses and Trainings
2023
2023Insights on Medicinal Chemistry: Reaxys for Bioactivity data and SAR analysis
Health&Medicine
Elsevier
2023
2023Advancing Chemistry and Pharmacy Research: Reaxys Advanced Search
Health&Medicine
Elsevier
2021
2021TÜBİTAK – BİDEB 2237-A PROGRAMI - Lisansüstü Danışmanlık Eğitimi (ATAOGEM)
Vocational Training
ATATÜRK ÜNİVERSİTESİ
2021
2021İlaç Tasarımında Yüksek Başarımlı Hesaplama Teknolojileri
Vocational Training
EuroCC-Türkiye Projesi
2021
2021IUGEN 18th Molecular Biology and Genetics Winter School
Other
İSTANBUL ÜNİVERSİTESİ
2020
2020Elsevier Turkiye 5N1K Online Seminer Serisi - Yayin YapmayaNasil Hazirlanabilirim?
Vocational Training
TUBITAK ULAKBIM EKUAL
2020
2020AB Ufuk2020 Marie Sklodowska Curie Alanı Bilgilendirme Semineri
Vocational Training
TUBİTAK
2019
2019Öğrenme ve Öğrenme Çalıştayları Modul 1
Vocational Training
ATATURK UNİVERSİTESİ
2019
2019Temel İş Sağlığı ve Güvenliği Eğitimi
Vocational Training
ATATÜRK ÜNİVERSİTESİ
2018
2018Biowaste Training
Vocational Training
University of Saskatchewan
2018
2018Biosafety
Vocational Training
University of Saskatchewan, Saskatoon, Canada
2018
2018Workplace Hazardous Material Information System 2015-WHMIS
Vocational Training
University of Saskatchewan, Saskatoon, Canada
2016
2016III. Uygulamalı Moleküler Biyoloji Teknikleri Lisansüstü Yaz Okulu
Vocational Training
ATATÜRK ÜNİVERSİTESİ DAYTAM
2016
20162. Bilgisayar Destekli İlaç Tasarımı Kursu
Vocational Training
Biruni Üniversitesi Eczacılık Fakültesi
2016
2016IV. Ulusal Farmasötik Kimya Kongresi
Health&Medicine
Türk Farmasötik ve Medisinal Kimya Derneği
2015
2015Proteinlerin Dinamik Simülasyonu: Temelleri ve Uygulamaları Yaz Kursu
Vocational Training
TOBB Ekonomi ve Teknoloji Üniversitesi
2015
20151. Bilgisayar Destekli İlaç Tasarımı Kursu (Uygulamalı)
Vocational Training
Biruni Üniversitesi Eczacılık Fakültesi
2015
2015Tübitak 1000 Programı Kapsamında Akademik Düzeyde Tübitak Projesi Hazırlama Eğitimi
Vocational Training
ATATÜRK ÜNİVERSİTESİ
2014
2014TÜBİTAK 2237-Projemi Yazıyorum Etkinliği
Vocational Training
ATATÜRK ÜNİVERSİTESİ
2014
2014Research Methodology Course
Vocational Training
ATATÜRK ÜNİVERSİTESİ TIP FAKÜLTESİ
2014
2014Patent-Faydalı Model Eğitim Semineri
Vocational Training
ATATÜRK ÜNİVERSİTESİ MÜHENDİSLİK FAKÜLTESİ
2011
2011Türk Farmasötik ve Medisinal Kimya Derneği Başarı Belgesi
Other
Türk Farmasötik ve Medisinal Kimya Derneği
2011
2011ISO 22000 Gıda Güvenliği Yönetim Sistemi Başdenetçi Sertifikası
Vocational Course
ALBERK DANIŞMANLIK
2011
2011ISO 9001:2008 Kalite Yönetim Sistemi Başdenetçi Sertifikası
Vocational Course
ALBERK DANIŞMANLIK
2010
2010cGMP - İlaç ve Kozmetik İyi İmalat Metodları
Vocational Course
Quality Academia Eğitim ve Danışmanlık
2008
2008ISO 9001:2000 KALİTE YÖNETİM SİSTEMİ - OHSAS 18001:2007- İÇ DENETÇİLİK
Vocational Course
NOBEL DANIŞMANLIK
Research Areas
Pharmacology and Therapeutics
Professional Sciences
Pharmaceutical Chemistry
Chemistry
Organic Chemistry
Academic Titles / Tasks
2021 - Continues
2021 - ContinuesAssociate Professor
Cukurova University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2020 - 2023
2020 - 2023Assistant Professor
Cukurova University, Eczacılık Fakültesi, Temel Eczacılık Bilimleri
2013 - 2020
2013 - 2020Research Assistant
Ataturk University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Managerial Experience
2022 - Continues
2022 - ContinuesRectorate Commissioner
Cukurova University, Eczacılık Fakültesi
2022 - Continues
2022 - ContinuesFakülte Kurulu Üyesi
Cukurova University, Eczacılık Fakültesi
2022 - Continues
2022 - ContinuesFakülte Yönetim Kurulu Üyesi
Cukurova University, Eczacılık Fakültesi
2022 - Continues
2022 - ContinuesBölüm Akademik Teşvik Değerlendirme Komisyonu Üyesi
Cukurova University, Eczacılık Fakültesi
2021 - Continues
2021 - ContinuesAkreditasyon, Sürekli Gelişim ve Yenilenme Kurulu Üyesi
Cukurova University, Eczacılık Fakültesi
2021 - Continues
2021 - ContinuesEğitim ve Müfredat Kurulu üyesi
Cukurova University, Eczacılık Fakültesi
2020 - 2021
2020 - 2021Head of Department
Cukurova University, Eczacılık Fakültesi, Temel Eczacılık Bilimleri
2020 - 2021
2020 - 2021Internship Committee Member
Cukurova University, Eczacılık Fakültesi
Non Academic Experience
2018 - 2018
2018 - 2018Bursiyer, konuk araştırmacı, (TUBITAK 2214-A Kapsamında)
University of Saskatchewan, College of Pharmacy and Nutrition, Department of Medicinal Chemistry, Saskatoon, Canada
2014 - 2014
2014 - 2014Bursiyer, konuk araştırmacı, (ERASMUS INTERN Kapsamında)
Polo Scientifico, Laboratorio di Chimica Bioinorganica, Universita degli Studi di Firenze,Sesto Fiorentino (Firenze), Italy
2013 - 2013
2013 - 2013İlaç Üretim Uzmanı
Neutec İlaç AŞ
2013 - 2013
2013 - 2013Solid İlaç Üretimi
Business Establishment Private, Neutec İlaç AŞ, İlaç Üretimi
2009 - 2012
2009 - 2012Kalite Kontrol ve Kalite Yönetim Müdürü
Aile ve Sosyal Politikalar Bakanlığı
2009 - 2009
2009 - 2009Stajyer
Other Public Institution, Refik Saydam Hıfzısıhha Araştırma Merkezi Başkanlığı, Analiz
2008 - 2008
2008 - 2008Stajyer
Business Establishment Private, DİNÇSA İLAÇ SANAYİ, Solid İlaç Üretimi
2008 - 2008
2008 - 2008Stajyer
Refik Saydam Hıfzısıhha Araştırma Merkezi Başkanlığı
2008 - 2008
2008 - 2008İlaç Üretimi ve Kalite Kontrol Stajyer
Dinçsa İlaç A.Ş.
Courses
Published journal articles indexed by SCI, SSCI, and AHCI
2024
2024Synergistic quantification of mixed insulin preparations using time domain NMR techniques
Alam H., Ozesme Taylan G., YAMALI C., ÖZTOP H. M.
Journal of Pharmaceutical and Biomedical Analysis
, vol.247, 2024 (SCI-Expanded)
2024
2024In Vitro Enzyme Activity and Molecular Docking Studies of Pyrazoline Derivatives as Monoamine Oxidase Inhibitors
Sakarya M. T., GÜL H. İ., YAMALI C., ÖZKAY Y., Tok T. T.
Pharmaceutical Chemistry Journal
, vol.58, no.3, pp.419-427, 2024 (SCI-Expanded)
2024
2024Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and antimicrobial agents.
Poyraz S., Dondas H. A., Yamali C., Belveren S., Demir Y., Aydinoglu S., et al.
Journal of biomolecular structure & dynamics
, vol.42, no.7, pp.3441-3458, 2024 (SCI-Expanded)
2024
2024Biological Activities and Drug-Likeness Properties of Phenol-Based Heterocyclic Compounds
YAMALI C., NENNİ M., Sakarya M. T., Sakagami H., GÜL H. İ.
Pharmaceutical Chemistry Journal
, 2024 (SCI-Expanded)
2023
2023Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design.
Yamali C., Gul M., Gul H. I.
Current topics in medicinal chemistry
, 2023 (SCI-Expanded)
2023
2023Design, synthesis, and assessment of pharmacological properties of indole-based fluorinated chalcones and their benzenesulfonamide analogs
Yamalı C., Sevin S., Nenni M., Tugrak Sakarya M., Uyar R., Aygul A., et al.
CHEMICAL PAPERS
, vol.77, no.12, pp.7903-7918, 2023 (SCI-Expanded)
2023
2023Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and antimicrobial agents
Poyraz S., Döndaş H. A., Yamalı C., Belveren S., Demir Y., Aydınoğlu S., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS , no.1, pp.1-18, 2023 (SCI-Expanded)
2023
2023Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease
Yamalı C., Donmez S.
MINI-REVIEWS IN MEDICINAL CHEMISTRY
, vol.1, no.1, pp.1, 2023 (SCI-Expanded)
2023
2023N-Benzoylthiourea-pyrrolidine carboxylic acid derivatives bearing an imidazole moiety: Synthesis, characterization, crystal structure, in vitro ChEs inhibition, and antituberculosis, antibacterial, antifungal studies
Poyraz S., Döndaş H. A., Sansano J. M., Belveren S., Yamalı C., Ülger M., et al.
JOURNAL OF MOLECULAR STRUCTURE , vol.1273, pp.134303, 2023 (SCI-Expanded)
2022
2022Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores.
Yamali C., Sakagami H., Satoh K., Bandow K., Uesawa Y., Bua S., et al.
Bioorganic chemistry
, vol.127, pp.105969, 2022 (SCI-Expanded)
2022
2022<p>Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies</p>
Yamali C., Gul H. I., Tugrak Sakarya M., Nurpelin Saglik B., Ece A., Demirel G., et al.
BIOORGANIC CHEMISTRY
, vol.124, 2022 (SCI-Expanded)
2021
2021Effects of a Novel Benzenesulfonamide 4-(3-(4-Bromophenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) on Antioxidant Enzymes and Hematological Parameters of Rainbow Trout (Oncorhynchus mykiss)
Ozgun D. O., ALAK G., UÇAR A., Bilginer S., GÜL H. İ., Kocaman M., et al.
PAKISTAN JOURNAL OF ZOOLOGY
, vol.53, no.6, pp.2083-2089, 2021 (SCI-Expanded)
2021
2021Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides.
Yamali C., Inci Gul H., Ozli G., Angeli A., Ballar Kirmizibayrak P., Erbaykent Tepedelen B., et al.
Bioorganic chemistry
, vol.115, pp.105194, 2021 (SCI-Expanded)
2021
2021Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.
Yamali C., Sakagami H., Uesawa Y., Kurosaki K., Satoh K., Masuda Y., et al.
European journal of medicinal chemistry
, vol.217, pp.113351, 2021 (SCI-Expanded)
2021
2021Biological activities of a newly synthesized pyrazoline derivative 4-(3-(4-bromophenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide (B4) compound on rainbow trout alevins, Oncorhynchus mykiss.
Ucar A., Ozmen Ozgun D., Alak G., Gul H. I., Kocaman M., Yamalı C., et al.
In vitro cellular & developmental biology. Animal
, vol.57, pp.17-20, 2021 (SCI-Expanded)
2021
2021Phenothiazine-based chalcones as potential dual-target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO-A, MAO-B)
Yamali C., Engin F. S., Bilginer S., Tuğrak M., Ozmen Ozgun D., Özli G., et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY
, vol.58, no.1, pp.161-171, 2021 (SCI-Expanded)
2020
2020Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes
Yamali C., Gül H. İ., Kazaz C., Levent S., Gülçin İ.
BIOORGANIC CHEMISTRY
, vol.96, 2020 (SCI-Expanded)
2020
2020Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors
YAMALI C., GÜL H. İ., Çakır T., Demir Y., GÜLÇİN İ.
LETTERS IN DRUG DESIGN & DISCOVERY
, vol.17, no.10, pp.1283-1292, 2020 (SCI-Expanded)
2020
2020Synthesis and bioactivities of 1-(4-hydroxyphenyl)-2-((heteroaryl)thio)ethanones as carbonic anhydrase I, II and acetylcholinesterase inhibitors
Yamali C., GÜL H. İ., Demir Y., KAZAZ C., GÜLÇİN İ.
TURKISH JOURNAL OF CHEMISTRY
, vol.44, no.4, pp.1058-1067, 2020 (SCI-Expanded)
2019
2019Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors
Yamali C., GÜL H. İ., Ece A., Bua S., Angeli A., Sakagami H., et al.
BIOORGANIC CHEMISTRY
, vol.92, 2019 (SCI-Expanded)
2019
2019Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity
Ozgun D. O., GÜL H. İ., Yamali C., Sakagami H., GÜLÇİN İ., Sukuroglu M., et al.
BIOORGANIC CHEMISTRY
, vol.84, pp.511-517, 2019 (SCI-Expanded)
2018
2018Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates
GÜL H. İ., Yamali C., Gunesacar G., Sakagami H., Okudaira N., Uesawa Y., et al.
MEDICINAL CHEMISTRY RESEARCH
, vol.27, no.10, pp.2366-2378, 2018 (SCI-Expanded)
2018
2018Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells
Badr G., GÜL H. İ., Yamali C., Mohamed A. A. M., Badr B. M., GÜL M., et al.
BIOORGANIC CHEMISTRY
, vol.78, pp.46-57, 2018 (SCI-Expanded)
2018
2018Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes
Gül H. İ., Yamali C., Bulbuller M., Kirmizibayrak P. B., Gül M., Angeli A., et al.
BIOORGANIC CHEMISTRY
, vol.78, pp.290-297, 2018 (SCI-Expanded)
2018
2018Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes
Yamali C., GÜL H. İ., Ece A., Taslimi P., GÜLÇİN İ.
CHEMICAL BIOLOGY & DRUG DESIGN
, vol.91, no.4, pp.854-866, 2018 (SCI-Expanded)
2018
2018New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors
GÜL H. İ., Yamali C., Sakagami H., Angeli A., Leitans J., Kazaks A., et al.
BIOORGANIC CHEMISTRY
, vol.77, pp.411-419, 2018 (SCI-Expanded)
2017
2017Microwave-assisted synthesis and bioevaluation of new sulfonamides.
Gul H. I., Yamali C., Yesilyurt F., Sakagami H., Kucukoglu K., Gulcin I., et al.
Journal of enzyme inhibition and medicinal chemistry
, vol.32, pp.369-374, 2017 (SCI-Expanded)
2017
2017Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents
Yamali C., Ozgun D. O., GÜL H. İ., Sakagami H., KAZAZ C., Okudaira N.
MEDICINAL CHEMISTRY RESEARCH
, vol.26, no.9, pp.2015-2023, 2017 (SCI-Expanded)
2017
2017Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl] benzenesulfonamides
GÜL H. İ., METE E., Eren S. E., Sakagami H., Yamali C., Supuran C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.32, no.1, pp.169-175, 2017 (SCI-Expanded)
2017
2017Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones
Yamali C., GÜL H. İ., Ozgun D. O., Sakagami H., Umemura N., KAZAZ C., et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
, vol.17, no.10, pp.1426-1433, 2017 (SCI-Expanded)
2016
2016Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines
Kucukoglu K., Oral F., Aydin T., Yamali C., Algul O., Sakagami H., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, pp.20-24, 2016 (SCI-Expanded)
2016
2016Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol
GÜL H. İ., Yamali C., Yasa A. T., Unluer E., Sakagami H., Tanc M., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, no.6, pp.1375-1380, 2016 (SCI-Expanded)
2016
2016Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects
GÜL H. İ., Kucukoglu K., Yamali C., BİLGİNER S., YUCA H., Ozturk I., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, no.4, pp.568-573, 2016 (SCI-Expanded)
2016
2016Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase
Ozgun D. O., Yamali C., GÜL H. İ., Taslimi P., GÜLÇİN İ., YANIK T., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, no.6, pp.1498-1501, 2016 (SCI-Expanded)
2016
2016Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2,3-dihydroinden-1-one and evaluation of their cytotoxicities
TUĞRAK M., Yamali C., Sakagami H., GÜL H. İ.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, no.5, pp.818-823, 2016 (SCI-Expanded)
2016
2016Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases
Yamali C., GÜL H. İ., Sakagami H., Supuran C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, pp.125-131, 2016 (SCI-Expanded)
2016
2016The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes
Yamali C., TUĞRAK M., GÜL H. İ., Tanc M., Supuran C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, no.6, pp.1678-1681, 2016 (SCI-Expanded)
2015
2015Synthesis of some 3(2H)-pyridazinone and 1(2H)-phthalazinone derivatives incorporating aminothiazole moiety and investigation of their antioxidant, acetylcholinesterase, and butyrylcholinesterase inhibitory activities
Yamali C., Gulcan H. O., Kahya B., Cobanoglu S., Sukuroglu M. K., Dogruer D. S.
MEDICINAL CHEMISTRY RESEARCH
, vol.24, no.3, pp.1210-1217, 2015 (SCI-Expanded)
2013
2013Synthesis of Some New 3(2H)-Pyridazinone Derivatives and Evaluation of their Analgesic-anti-inflammatory and Antimicrobial Activities
Sukuroglu M., Yamali C., Tiryaki D., Onurdag F. K., Akkol E., Dogruer D. S.
LETTERS IN DRUG DESIGN & DISCOVERY
, vol.10, no.6, pp.507-514, 2013 (SCI-Expanded)
Articles Published in Other Journals
2023
2023IMIDAZOLINONE-BASED SULFONAMIDE DERIVATIVES: SYNTHESIS, CHARACTERIZATION, AND INHIBITORY PROPERTY AGAINST SOME METABOLIC ENZYMES
Tuğrak Sakarya M., Gul H. I., Yamali C., Demir Y., Gulcin i.
Ankara Üniversitesi Eczacılık Fakültesi Dergisi
, vol.47, no.3, pp.915-926, 2023 (Scopus)
2023
2023Molecular docking studies and biological activities of benzenesulfonamide-based thiourea and thiazolidinone derivatives targeting cholinesterases, α-glucosidase, and α-amylase enzymes
TUĞRAK SAKARYA M., GÜL H. İ., YAMALI C., TASLIMI P., TAŞKIN TOK T.
The Turkish Chemical Society
, vol.10, no.2, pp.385-424, 2023 (Peer-Reviewed Journal)
2021
2021Inhibitory effects of novel benzamide derivatives towards acetylcholinesterase enzyme
YAMALI C., GÜL H. İ., LEVENT S., DEMİR Y.
Journal of the Turkish Chemical Society Section A: Chemistry
, vol.8, no.2, pp.429-434, 2021 (Scopus)
2020
2020Inhibitory effects of the chalcones towards carbonic anhydrase I, II andacetylcholinesterase enzymes
TUĞRAK M., YAMALI C., GÜL H. İ., DEMİR Y.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi , vol.13, no.3, pp.1138-1146, 2020 (Peer-Reviewed Journal)
2020
2020Cytotoxic effects of Mannich bases via induction of caspase-3 pathway on human oral squamous cell carcinoma
YAMALI C., GÜL H. İ.
Journal of the Turkish Chemical Society Section A: Chemistry
, vol.8, no.1, pp.187-194, 2020 (Scopus)
Refereed Congress / Symposium Publications in Proceedings
2023
2023Monoamine oxidase inhibition and toxicity evaluation of phenylurea-bearing hydrazones
YAMALI C., DEMİREL G.
6th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2023) October 11-13, 2023., Ankara, Turkey, 11 - 13 October 2023
2023
2023A PRELIMINARY STUDY OF CHOLINESTERASE INHIBITION AND CYTOTOXICITY EVALUATION OF INDOLEBASED CHALCONE DERIVATIVE
YAMALI C., DEMİREL G.
International Multidisciplinary Symposium on Drug Research and Development DRD 2023, İzmir, Turkey, 4 - 06 May 2023
2022
2022Paraoxonase Enzyme Inhibition Effects Of Sulfonamide Bearing Compounds
DEDEOĞLU N., YAMALI C.
5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022) November 23-25, 2022., Turkey, 23 November 2022
2022
2022The design of modern tacrine-based drug candidates in the treatment of Alzheimer's disease
Dönmez Ş., YAMALI C.
5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022) November 23-25, 2022, Turkey, 23 November 2022
2021
2021The Effects of Some Secondary Sulfonamide Derivatives on Lactoperoxidase Enzyme Activity
DEDEOĞLU N., YAMALI C.
6th INTERNATIONAL CONGRESS on APPLIED BIOLOGICAL SCIENCE, Turkey, 8 - 09 December 2021, pp.33-38
2020
2020Pirazol-Benzensülfonamit Grubu Taşıyan Schiff Bazı Türevinin Sentezi ve Karbonik Anhidraz Enzimleri Üzerine Etkisi
YAMALI C.
32. Ulusal Kimya Kongresi, Turkey, 17 - 19 September 2020
2020
2020THE ROLE OF CARBONIC ANHYDRASE ENZYMES INANTICANCER DRUG RESEARCH
YAMALI C.
EURO ASIA 7th. INTERNATIONAL CONGRESS ON APPLIED SCIENCES, 21 - 22 August 2020
2020
2020Synthesis of novel (E)-1-(4-hydroxy-3-((4-phenylpiperazin-1-yl)methyl)phenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one as a selective cytotoxic agent.
YAMALI C.
INSAC - Natural and Health Sciences Congress 2020, 22 - 23 May 2020
2020
2020Synthesis of potential bioactive pyrazole-carboxamides
YAMALI C., GÜL H. İ.
3rd International Eurasian Conference on Biological and Chemical Sciences(EurasianBioChem 2020)March 19-20, 2020 / Ankara, Turkey, 19 - 20 March 2020
2020
2020-1-(4-Sülfamoilfenil)-5-(tiyofen-2-il)-1H-pirazol-3-(N-sübstitüe) karboksamitlerin sentezi ve kimyasal yapılarının aydınlatılması
YAMALI C., ÖZLİ G., GÜL H. İ.
3rd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2020), March 19-20, 2020 Ankara, Turkey, 19 - 20 March 2020
2019
2019Pyrazole-Benzensulfonamides: Inhibitory Effects On Cancer-Associated Carbonic Anhydrase IX (CA IX) Isoenzyme
YAMALI C., GÜL H. İ., Supuran C. T.
ISPEC- 5 th INTERNATIONAL CONFERENCE ON ENGINEERING NATURAL SCIENCES, 20 - 22 December 2019
2018
2018Inhibitory Effects of Isatin Mannich Bases on Carbonic Anhydrases, Acetylcholinesterase,and Butyrylcholinesterase
ÖZMEN ÖZGÜN D., YAMALI C., GÜL H. İ., TASLİMİ P., GÜLÇİN İ., YANIK T., et al.
2018 5th International Conference on Chemical and Biological Sciences (ICCBS 2018) BUCHAREST CONFERENCE, ROMANIA, Romania, 7 - 09 March 2018
2017
2017Structure Elucidation Of 1-(2,5/3,5-difluorophenyl)-3 (2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones
KAZAZ C., GÜL H. İ., YAMALI C.
The International Workshop on the Application of NMR in Pharmaceutics, Phytotherapeutics and Medicine, Bezmialem Vakıf Üniversitesi, İstanbul, Turkey, İstanbul, Turkey, 15 - 17 November 2017
2017
2017Bioactivities of Isatin Mannich Bases
ÖZMEN ÖZGÜN D., GÜL H. İ., YAMALI C.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, 5 - 07 October 2017
2017
20171,5-Bis(4-hydroxy-3-(aminomethyl)phenyl)penta-1,4-dien-3-ones: Bis Mannich Bases as Anticancer Agents
GÜL H. İ., YAMALI C., Sakagami H.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, Erzurum, Turkey, 5 - 07 October 2017
2017
2017Synthesis of Novel Pyrazolines and Their Inhibitory Effects on hCA IX and XII Isoenzymes
GÜL H. İ., YAMALI C., Supuran C. T.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, 5 - 07 October 2017
2017
2017Synthesis, Molecular Modeling and Biological Evaluation of4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides
YAMALI C., GÜL H. İ., ECE A., GÜLÇİN İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017, Erzurum, Turkey, 5 - 07 October 2017
2017
2017Design, Synthesis and Bioevaluation of Pyrazoline Derivatives Bearing Primary Sulfonamide As Carbonic Anhydrase Inhibitors
GÜL H. İ., YAMALI C., ÖZMEN ÖZGÜN D., GÜLÇİN İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, 5 - 07 October 2017
2017
2017Carbonic Anhydrase Isoenzymes inhibition effects of new pyrazoline benzenesulfomamides
ÖZMEN ÖZGÜN D., GÜL H. İ., YAMALI C., GÜLÇİN İ., SUPURAN C. T.
3RD SARELLİTE MEETING ON CARBONIC ANHYDRASE NEW TRENDS IN CARBONIC ANHYDRASES RESEARCH, Florence, Italy, 24 - 27 May 2017
2016
2016Synthesis and Cytotoxic Activities of Difluoro Dimethoxy Chalcones
ÖZMEN ÖZGÜN D., GÜL H. İ., YAMALI C., Sakagami H.
4th International BAU Drug Design Congress,Istanbul, İstanbul, Turkey, 13 - 15 October 2016
2016
2016Synthesis and Cytotoxicities of New Sulfonamides
GÜL H. İ., YAMALI C., Sakagami H.
4th International Bahçeşehir University (BAU) Drug Design Congress, Istanbul, İstanbul, Turkey, 13 - 15 October 2016
2016
2016Synthesis Cytotoxities and Docking Studies of New Chalcones
YAMALI C., GÜL H. İ., ÖZMEN ÖZGÜN D., TUTAR Y.
4th International Bahçeşehir University (BAU) Drug Design Congress, İstanbul, Turkey, 13 - 15 October 2016
2016
2016hCA IX and XII Inhibition Studies of 4 -3-4-Hydroxyphenyl -5-aryl-4, 5-dihydro pyrazol-1-yl benzenesulfonamides
METE E., GÜL H. İ., YAMALI C., Supuran C. T.
4th International BAU Drug Design Congress, Istanbul, İstanbul, Turkey, 13 - 15 October 2016
2016
20161 İndanon Türevi Mono Mannich Bazlarının Sentezi ve Antikanser Aktiviteleri
TUĞRAK M., YAMALI C., GÜL H. İ.
III. Uygulamalı Moleküler Biyoloji Teknikleri Lisansüstü Yaz Okulu, DAYTAM, Erzurum, Erzurum, Turkey, 19 - 22 May 2016
2015
2015Design synthesis and cytotoxicities of halogen bearing new phenolic bis Mannich bases
YAMALI C., GÜL H. İ., Hiroshi S.
11th International Symposium on Pharmaceutical Sciences (ISOPS-11), Ankara, Turkey, Ankara, Turkey, 9 - 12 June 2015
2014
2014Synthesis of new bis Mannich bases of 1,3-diphenyl-2-propene-1- ones by the microwave irradiation and spectral analysis
YAMALI C., GÜL H. İ.
1th International Congress: From Drug Discovery to Drug Delivery, Greece, Athens, Atina, Greece, 13 - 15 November 2014
2014
2014New mono Mannich derivatives of 2-4-hydroxy-3-aminomethyl benzylidene indan 1 ones synthesis and cytotoxic activities
TUĞRAK M., GÜL H. İ., YAMALI C., SAKAGAMI H.
1th International Congress: From Drug Discovery to Drug Delivery, Greece, Athens, 13 - 15 November 2014
Books & Book Chapters
2023
2023Current Research in Pharmacy and Pharmaceutical Sciences
Yamalı C. (Editor)
Akademisyen Kitabevi, Adana, 2023
2022
2022COVID-19 HASTALIĞINI HEDEF ALAN AJANLARIN TASARIMINDA İLAÇ YENİDEN KONUMLANDIRMA (DRUG REPURPOSING) UYGULAMALARI
Dağlı T., YAMALI C.
in: Disiplinlerarası Tıp ve Sağlık Bilimleri Kavramlar, Araştırmalar ve Uygulama, Nizami Duran, Meriç Eraslan, Editor, Livre de Lyon, pp.307-328, 2022
2022
2022CHAPTER XV. RECENT DRUG DEVELOPMENT STUDIES ON NOVEL AND SELECTIVE COX-2 INHIBITORS
Baltacıoğlu O., Dönmez Ş., YAMALI C.
in: Interdisciplinary Medicine and Health Sciences Concepts, Researches and Practice, Erdinç Yalın, Meriç Eraslan, Editor, Livre de Lyon, pp.157-178, 2022
Supported Projects
2021 - 2022
2021 - 20223-(1H-İndol-3-il)-1-aril-2-propen-1-on türevlerinin sentezi kimyasal yapılarının aydınlatılması ve antibakteriyel etkilerinin araştırılması
Project Supported by Higher Education Institutions
YAMALI C. (Executive), TARI Ö., GÜL H. İ., ÜLGER M.
2021 - 2022
2021 - 2022Fonksiyonel grup bulunduran polisübstitüe pirolidin halkası taşıyan potansiyel biyoaktif 4-[(3-(sübstitüepirolidin-1-karbonil)-5-(tiyofen-2-il)-1H-pirazol-1il] benzen sülfonamidlerin sentezi ve biyoaktivitelerinin incelenmesi
Project Supported by Higher Education Institutions
DÖNDAŞ H. A. (Executive), YAMALI C., AYGÜL A., AYDINOĞLU S., POYRAZ S., BELVEREN S.
2019 - 2021
2019 - 2021Karbonik Anhidraz IX Enzimini Hedefleyen Yeni Pirazol-Karboksamitlerin Sentezi, Sitotoksik ve Karbonik Anhidraz İnhibe Edici Etkilerinin Araştırılması-219S076
TUBITAK Project
Yamalı C. (Executive), Gül H. İ., Özli G.
2017 - 2020
2017 - 2020Pirazol-Benzensülfonamit Artığı Taşıyan Çeşitli Bileşiklerin Sentezi, Yapılarının Aydınlatılması Ve Anikanser Etkilerinin AraştırılmasıPRJ2017/10F. Mülkiyet
Project Supported by Higher Education Institutions
Yamalı C., Gül H. İ.(Executive)
2016 - 2017
2016 - 2017Fenotiyazin halkası taşıyan şalkon türevlerinin tasarımı sentezi ve sitotoksik aktivitelerinin araştırılması
Project Supported by Higher Education Institutions
Yamalı C., Gül H. İ.(Executive), Özli G.
2015 - 2017
2015 - 20174(3 -Diflorofenil -5- dimetoksifenil -4,5- dihidro-1H-pirazol-1-il) benzensülfonamid türevlerinin sentezi ve karbonik anhidraz inhibisyon aktivitelerinin araştırılması Proje No:BAP 2015 078
Project Supported by Higher Education Institutions
Yamalı C., Gül H. İ.(Executive), Özmen Özgün D.
2015 - 2016
2015 - 2016Yeni fenolik bis Mannich bazlarının tasarımı sentezi ve sitotoksik aktivitelerinin araştırılması Proje No 2015 322
Project Supported by Higher Education Institutions
Yamalı C., Gül H. İ.(Executive)
2015 - 2016
2015 - 20164 (3-Substitüefenil-2 -Tiyenil -5 -Trimetoksifenil -4, 5-Dihidro-1H-Pirazol-1-ilBenzensülfonamit Taşıyan Bileşiklerin Tasarımı Sentezi Sitotoksisite ve Karbonik Anhidraz Inhibisyon Etkilerinin Araştırılması Proje No: TÜBİTAK 115S694
TUBITAK Project
Yamalı C., Gül H. İ.(Executive)
2014 - 2015
2014 - 20151H-Indol-2,3- dion Halkası Taşıyan Potansiyel Biyoaktif Mannich Bazlarının Sentezi ve Karbonik Anhidraz Aktivitelerinin Araştırılması BAP FEF 14 009
Project Supported by Higher Education Institutions
Yamalı C., Gül H. İ., Özmen Özgün D., Yanık T.(Executive)
Patent
2017
2017Pirazol-Benzensülfonamit Çekirdeği Taşıyan Potansiyel Antikanser Etkili Bileşiklerin Sentezi, Yapılarının Aydınlatılması Ve Sitotoksik Aktiviteleri (Araştırma raporu bekleniyor, süreç devam ediyor)
Patent
Pending / Applied, The Invention Recourse Number: TR2017006371 , Standard Registration
Activities in Scientific Journals
2022 - Continues
2022 - ContinuesCurrent Topics In Medicinal Chemistry
Evaluation Committee Member
2019 - Continues
2019 - ContinuesJournal of Drug Design and Medicinal Chemistry
Evaluation Committee Member
2020 - 2021
2020 - 2021Current Medicinal Chemistry
Evaluation Committee Member
2019 - 2021
2019 - 2021Current Pharmaceutical Biotechnology
Evaluation Committee Member
Memberships / Tasks in Scientific Organizations
2026 - Continues
2026 - ContinuesTürk Farmasötik ve Medisinal Kimya Derneği
Member
2023 - Continues
2023 - ContinuesCOST (European Cooperation in Science and Technology) - CA21111
Member
2023 - Continues
2023 - ContinuesCOST (European Cooperation in Science and Technology) CA21164 [WG3]
Member
2023 - Continues
2023 - ContinuesCOST (European Cooperation in Science and Technology) CA21145 [WG3]
Member
2020 - Continues
2020 - ContinuesAmerican Chemical Society
Member
2016 - Continues
2016 - ContinuesFarmasötik Bilimler Ankara Derneği (FABAD)
Member
Scientific Refereeing
February 2024
February 2024DRUG DEVELOPMENT RESEARCH
SCI Journal
January 2024
January 2024CHEMISTRY CENTRAL JOURNAL
SCI Journal
November 2023
November 2023CHEMICAL BIOLOGY AND DRUG DESIGN
SCI Journal
September 2023
September 2023ANKARA UNIVERSITESI ECZACILIK FAKULTESI DERGISI
National Scientific Refreed Journal
April 2023
April 2023Journal of Faculty of Pharmacy of Ankara University
Other Indexed Journal
November 2022
November 2022EURASIAN JOURNAL OF MEDICINE AND ONCOLOGY
National Scientific Refreed Journal
October 2022
October 2022CURRENT TOPICS IN MEDICINAL CHEMISTRY
SCI Journal
October 2022
October 2022JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
SCI Journal
September 2022
September 2022ARABIAN JOURNAL OF CHEMISTRY
SCI Journal
August 2022
August 2022JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
SCI Journal
July 2022
July 2022CURRENT TOPICS IN MEDICINAL CHEMISTRY
SCI Journal
June 2022
June 2022CURRENT MEDICINAL CHEMISTRY
SCI Journal
June 2022
June 2022CURRENT MEDICINAL CHEMISTRY
SCI Journal
May 2022
May 2022MINI-REVIEWS IN MEDICINAL CHEMISTRY
SCI Journal
May 2022
May 2022ARABIAN JOURNAL OF CHEMISTRY
SCI Journal
May 2022
May 2022Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
TÜSEB, Turkey
May 2022
May 2022Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
TÜSEB, Turkey
February 2022
February 2022JOURNAL OF HETEROCYCLIC CHEMISTRY
Journal Indexed in SCI-E
January 2022
January 2022ONLİNE TÜRK SAĞLIK BİLİMLERİ DERGİSİ
National Scientific Refreed Journal
January 2022
January 2022JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Journal Indexed in SCI-E
November 2021
November 2021CURRENT TOPICS IN MEDICINAL CHEMISTRY
SCI Journal
August 2021
August 2021SYNTHETIC METALS
Journal Indexed in SCI-E
July 2021
July 2021JOURNAL OF HETEROCYCLIC CHEMISTRY
Journal Indexed in SCI-E
July 2021
July 2021CURRENT MEDICINAL CHEMISTRY
Journal Indexed in SCI-E
May 2021
May 2021FUTURE MEDICINAL CHEMISTRY
Journal Indexed in SCI-E
May 2021
May 2021Journal of Applied Pharmaceutical Science
Other Indexed Journal
March 2021
March 2021MINI-REVIEWS IN MEDICINAL CHEMISTRY
Journal Indexed in SCI-E
March 2021
March 2021Journal of the Turkish Chemical Society Section A: Chemistry
Other Indexed Journal
February 2021
February 2021BMC Chemistry
Other Indexed Journal
January 2021
January 2021EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
SCI Journal
December 2020
December 2020CURRENT MEDICINAL CHEMISTRY
SCI Journal
December 2020
December 2020Project Supported by Higher Education Institutions
BAP Research Project, Ataturk University, Turkey
November 2020
November 2020ARABIAN JOURNAL OF CHEMISTRY
SCI Journal
October 2020
October 2020JOURNAL OF THE TURKİSH CHEMİCAL SOCİETY, SECTİON A: CHEMİSTRY
National Scientific Refreed Journal
October 2020
October 2020Journal of Applied Pharmaceutical Science
Other Indexed Journal
February 2020
February 2020Journal Of applied Pharmaceutical Science
Other Indexed Journal
January 2020
January 2020Organic Communications
Journal Indexed in ESCI
January 2020
January 2020BIOORGANIC CHEMISTRY
SCI Journal
November 2019
November 2019INORGANIC AND NANO-METAL CHEMISTRY
SCI Journal
August 2019
August 2019JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
SCI Journal
June 2019
June 2019MINI-REVIEWS IN MEDICINAL CHEMISTRY
SCI Journal
June 2019
June 2019JOURNAL OF HETEROCYCLIC CHEMISTRY
SCI Journal
May 2019
May 2019MINI-REVIEWS IN MEDICINAL CHEMISTRY
SCI Journal
November 2018
November 2018ARCHIV DER PHARMAZIE
SCI Journal
October 2018
October 2018JOURNAL OF MOLECULAR STRUCTURE
SCI Journal
Scientific Consultations
2023 - 2023
2023 - 2023Project Consultancy
TÜBİTAK
Cukurova University, Eczacılık Fakültesi, Temel Eczacılık Bilimleri, Turkey
2022 - 2022
2022 - 2022Project Consultancy
Türkiye Sağlık Enstitüleri Başkanlığı (TÜSEB)
Cukurova University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri, Turkey
Tasks In Event Organizations
Aralık 2020
Aralık 20205. Uluslararası Tıp ve Sağlık Bilimleri Kongresi ( UTSAK)
Scientific Congress
Yamalı C.
Turkey
Ağustos 2020
Ağustos 20204. Uluslararası Tıp ve Sağlık Bilimleri Kongresi ( UTSAK)
Scientific Congress
Yamalı C.
Turkey
Ağustos 2020
Ağustos 2020EURO ASIA 7th. INTERNATIONAL CONGRESS ON APPLIED SCIENCES
Scientific Congress
Yamalı C.
Turkey
Mobility Activity
2018 - 2018
2018 - 2018Research Scholarship Program
Scientific Research
University of Saskatchewan, Canada
2014 - 2014
2014 - 2014Erasmus Programme
Research During Graduate Education
Universita Degli Studi di Firenze, Italy
Awards
May 2022
May 2022TÜBİTAK Q1 YAYIN TEŞVİK ÖDÜL
Tübitak
October 2021
October 2021TÜBİTAK Q1 YAYIN TEŞVİK ÖDÜLÜ
Tübitak
August 2020
August 2020EFMC Photo Competition 2020
European Federation For Medicinal Chemistry
June 2020
June 2020Proje Bilimsel Teşvik Ödülü
Atatürk Üniversitesi
Congress and Symposium Activities
26 September 2023 - 26 September 2023
26 September 2023 - 26 September 202316th EFMC-YSN MedChemBioOnline-Young Scientists Network of the European Federation for Medicinal chemistry and Chemical biology (EFMC-YSN)
Audience
Antwerp-Belgium
Scholarships
2018 - 2019
2018 - 20192214-A YURTDIŞI ARAŞTIRMA BURS PROGRAMI-UNIVERSITY OF SASKATCHEWAN, CANADA
TUBITAK
2014 - 2014
2014 - 2014