Mannose-Binding Lectin 2 Gene Polymorphism in PANDAS Patients


GÜL ÇELİK G. , TAŞ ARSLAN D. , YOLGA TAHİROĞLU A. , ERKEN E. , SEYDAOĞLU G. , Ray P. C. , ...Daha Fazla

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.56, ss.99-105, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 56 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.29399/npa.22811
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Sayfa Sayıları: ss.99-105

Özet

Introduction: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), a subgroup of obsessive-compulsive disorder (OCD), has received much attention even though the specific underlying mechanisms remain unknown. Mannose-binding lectin (MBL) is a key factor in the innate immune response. The aim of this study was to investigate the role of MBL2 gene polymorphisms in pediatric OCD patients diagnosed as PANDAS, PANDAS-Variant and non-PANDAS.