REVERSIBLE HEMATOLOGICAL AND BIOCHEMICAL TOXIC EFFECTS OF AZOXYSTROBIN AND DIFENCONAZOLE MIXTURE EXPOSURES IN OREOCHROMIS NILOTICUS UNDER INCREASED HEAT STRESS


Creative Commons License

Oruç E.

V. INTERNATIONAL AGRICULTURAL, BIOLOGICAL, LIFE SCIENCE CONFERENCE, Edirne, Türkiye, 18 Eylül - 23 Kasım 2023, ss.1216-1223

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Edirne
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.1216-1223
  • Çukurova Üniversitesi Adresli: Evet

Özet

As one of the fastest growing sectors, aquaculture contributes to global food security. While pesticides play an important role in improving land productivity and food quality for a growing world population, especially in developing countries, their presence in agricultural drainage is a serious risk to all components of aquatic ecosystems. Additionally, there is a high risk that environmental contaminants will enter the human food chain and threaten public health. Therefore, there is an increasing need to find reliable approaches to rapidly determine the conditions of aquaculture ecosystems exposed to agricultural runoff and assess fish health and welfare. In addition to increases in pollutant inputs, increasing surface water temperatures due to climate change are affecting the physical condition of the aquatic system and coastal systems worldwide. Difenoconazole is a typical triazole fungicide used for the control of fungal disease in vegetables, grains and other field crops. Azoxystrobin is the most widely used fungicide worldwide. Although temperature is an important factor in toxicity, there are not enough studies to elucidate the metabolism related to the effects of temperature on pesticide toxicity. Therefore, the effects of pesticide exposures to azoxystrobin and difenconazole mixture (0.5ppb, 5 ppb, 10 ppb) under heat stress (22ºC and 30ºC) on defense mechanisms in Oreochromis niloticus blood tissue and the reversibility of these effects was examined in order to evaluate the health status of aquatic creatures and determine water quality. In this study, it was determined that hematological, enzymatic and metabolic responses occurred in O. niloticus against exposure to the pesticide mixture azoxystrobin and difenconazole.