The analysis of lncRNA HOTAIR rs12826786 C > T polymorphism and gastric cancer susceptibility in a Turkish population: lack of any association in a hospital-based case-control study

Ulger, YAKUP; Dadas, E.; Kaya, B.; Sumbul, A.; Genc, A.; Bayram, S.

doi:10.1007/s11845-017-1596-x

The analysis of lncRNA HOTAIR rs12826786 C > T polymorphism and gastric cancer susceptibility in a Turkish population: lack of any association in a hospital-based case-control study

Atıf İçin Kopyala

Ulger Y., Dadas E., Kaya B. Y., Sumbul A. T., Genc A., Bayram S.

IRISH JOURNAL OF MEDICAL SCIENCE, cilt.186, sa.4, ss.859-865, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 186 Sayı: 4
Basım Tarihi: 2017
Doi Numarası: 10.1007/s11845-017-1596-x
Dergi Adı: IRISH JOURNAL OF MEDICAL SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.859-865
Çukurova Üniversitesi Adresli: Hayır

Özet

The HOX transcript antisense intergenic RNA (HOTAIR), a well-known long noncoding RNA (lncRNA), has been widely identified to participate in pathogenesis of multiple cancers. An aberrant up-regulation and biological functions have been observed in gastric cancer (GC). A common single nucleotide polymorphism (SNP) (rs12826786 C > T) at the HOTAIR has been reported to influence HOTAIR expression, but its association with GC has yet to be investigated in Turkish population.