Elixir Hormones and Signaling, cilt.117, sa.2018, ss.50032-50037, 2018 (Diğer Kurumların Hakemli Dergileri)
Recent developments in the molecular biology have provided some specific molecular
markers which are generally used to define a specific region of genome. In genetic
analyses, three types of markers are used as morphological, protein and DNA markers.
After the discovery of polymerase chain reaction (PCR), PCR-based markers have been
begun to be more preferred. Studies of genetic characterization have inconsiderable
importance in the studies such as determining the level of inter and intra- population
genetic diversity, developing protection programs, domestication, and determination of
migration routes. In genetic characterization studies, the different biochemical marker
systems, alloenzymes, mitochondrial DNA, and Y chromosome specific molecules are
used. DNA markers, particularly polymorphic microsatellite markers, constitute the most
preferable system in PCR applications. New molecular biology techniques enable
analysis of single nucleotide polymorphism to be able to made faster and economically
and be used together with microsatellites.