Klinik Psikiyatri Dergisi, cilt.23, sa.3, ss.302-312, 2020 (ESCI)
Objective: Impulsive behaviors that adversely affect prognosis in bipolar disorder may persist in the euthymic period. Anxiety sensitivity is a protective factor for impulsive behaviors. In this study, we aimed to investigate the relationship between anxiety sensitivity and impulsive behaviors in bipolar disorder and the clinical features that may be effective in this relationship. Method: Seventy euthymic bipolar patients, according to the DSM-5 criteria, and 69 healthy volunteers with no comorbid mental disorders were included in the study. Sociodemographic data form, the Hamilton Depression Scale, Young Mania Rating Scale, Perceived Stress Scale, Anxiety Sensitivity Index-3, and UPPS Impulsive Behavior Scale were filled out. Results: The perceived stress level, social and cognitive sub-dimensions, and total scores of the Anxiety Sensitivity Index-3, and scores of the urgency and sensation seeking subscales of the Impulsive Behavior Scale were higher in patients than in healthy controls (p<0.001 for each). The perceived stress level was correlated with the total score of the Anxiety Sensitivity Index-3 and three sub-dimensions (p <0.001 for each). The perceived stress was a full mediator in the relationship between anxiety sensitivity and sensation seeking. Discussion: In this study, we found that euthymic bipolar patients showed different characteristics in terms of perceived stress, anxiety sensitivity, and impulsive behaviors than healthy controls. The mediating effect of perceived stress on the relationship between anxiety sensitivity and sensation seeking supports the hypothesis that impulsive behaviors will decrease with increased anxiety sensitivity and perceived stress levels.