Exon 2: Is it the good police in familial mediterranean fever?


Bilge S. Y. , Solmaz D., Senel S., Emmungil H., KILIÇ L., Oner S. Y. , ...Daha Fazla

EUROPEAN JOURNAL OF RHEUMATOLOGY, cilt.6, ss.34-37, 2019 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 6 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/eurjrheum.2018.18115
  • Dergi Adı: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Sayfa Sayıları: ss.34-37

Özet

Objective: Familial Mediterranean fever (FMF) is the most common autoinflammatory disease. Most of the identified disease-causing mutations are located on exon 10. As the number of studies about the effect of the exonal location of the mutation and its phenotypic expression is limited, we aimed to investigate whether the exonic location of the Mediterranean fever (MEFV) mutation has an effect on the clinical manifestation in patients with FMF.