Exon 2: Is it the good police in familial mediterranean fever?

Bilge, Sule; Solmaz, Dilek; Senel, Soner; Emmungil, Hakan; KILIÇ, LEVENT; Oner, Sibel; Yidiz, Fatih; Yilmaz, Sedat; Bozkirli, Duygu; Tufan, Muge; YILMAZ, SEMA; Yazisiz, Veli; Pehlivan, Yavuz; Bes, Cemal; ÇETİN, GÖZDE; Erten, Sukran; Gonullu, Emel; Sahin, Fezan; Akar, Servet; AKSU, KENAN; KALYONCU, UMUT; Direskeneli, Haner; ERKEN, EREN; Kisacik, Bunyamin; Sayarlioglu, Mehmet; Cinar, Muhammed; KAŞİFOĞLU, TİMUÇİN; Sari, Ismail

doi:10.5152/eurjrheum.2018.18115

Exon 2: Is it the good police in familial mediterranean fever?

Bilge S. Y., Solmaz D., Senel S., Emmungil H., KILIÇ L., Oner S. Y., ...More

EUROPEAN JOURNAL OF RHEUMATOLOGY, vol.6, no.1, pp.34-37, 2019 (ESCI, TRDizin)

Publication Type: Article / Article
Volume: 6 Issue: 1
Publication Date: 2019
Doi Number: 10.5152/eurjrheum.2018.18115
Journal Name: EUROPEAN JOURNAL OF RHEUMATOLOGY
Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Page Numbers: pp.34-37
Çukurova University Affiliated: Yes

Abstract

Objective: Familial Mediterranean fever (FMF) is the most common autoinflammatory disease. Most of the identified disease-causing mutations are located on exon 10. As the number of studies about the effect of the exonal location of the mutation and its phenotypic expression is limited, we aimed to investigate whether the exonic location of the Mediterranean fever (MEFV) mutation has an effect on the clinical manifestation in patients with FMF.