Ankaferd Blood Stopper Decreases Postoperative Bleeding and Number of Transfusions in Patients Treated with Clopidogrel: A Double-blind, Placebo-controlled, Randomized Clinical Trial

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Akpinar M. B., Atalay A., Atalay H., Dogan O. F.

HEART SURGERY FORUM, vol.18, no.3, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1532/hsf.1256
  • Journal Name: HEART SURGERY FORUM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Çukurova University Affiliated: Yes

Abstract

Background: The risk of reoperation due to bleeding after open heart surgery is 2.2%-4.2%. Extracorporeal circulation and emergency operations are the important risk factors. In coronary artery bypass graft (CABG) patients who are treated preoperatively with antiplatelets plus clopidogrel are the sources of postoperative bleeding. The aim of this study was to research the effect of local Ankaferd blood stopper (ABS) to prevent mediastinal bleeding in on-pump CABG patients who were treated with clopidogrel and acetylsalicylic acid (ASA) preoperatively.