Effects of Metal (Ag, Cd, Cr, Cu, Zn) Exposures on Some Enzymatic and Non-Enzymatic Indicators in the Liver of Oreochromis niloticus

Oner M., Atli G., CANLI M.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, cilt.82, sa.3, ss.317-321, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 82 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00128-008-9577-4
  • Dergi Adı: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.317-321
  • Anahtar Kelimeler: Heavy metals, Liver, Oreochromis niloticus, -SH group, Transaminases, OXIDATIVE STRESS, BETA-NAPHTHOFLAVONE, CADMIUM EXPOSURE, NILE TILAPIA, RESPONSES, PREEXPOSURE, COPPER, BIOMARKERS, METABOLISM, TOXICITY
  • Çukurova Üniversitesi Adresli: Evet

Özet

Freshwater fish Oreochromis niloticus exposed to 0.05 mu g/mL of Cu, Cd, Zn, Ag and Cr for up to 30 days. Only Ag, which exceeded environmentally realistic concentrations by a factor of > 100 caused fish mortality within this period. Metals increased aspartate transaminase (AST) activity, while they decreased alanine transaminase (ALT) activity, except Cr exposure. Concentrations of free -SH group decreased whereas protein concentrations did not alter following metal exposures. Detectable metal accumulation occurred in the liver of Cd, Cu and Zn exposed fish. This study emphasized that both enzymatic and non-enzymatic mechanisms may be useful in understanding the degree of metal toxicity in fish liver.