Copy For Citation
Ozeren M., Sucu N., Tamer L., Aytacoglu B., Bayri O., DÖNDAŞ H. A., ...More
PHARMACOLOGICAL RESEARCH, vol.52, no.3, pp.258-263, 2005 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
52
Issue:
3
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Publication Date:
2005
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Doi Number:
10.1016/j.phrs.2005.04.002
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Journal Name:
PHARMACOLOGICAL RESEARCH
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.258-263
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Keywords:
caffeic acid phenethyl ester, St. Thomas solution, antioxidants, myocardial reperfusion injury, scavenger, OXIDATIVE STRESS, ALPHA-TOCOPHEROL, NITRIC-OXIDE, MYELOPEROXIDASE
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Çukurova University Affiliated:
No
Abstract
Background and aim of study: Cardioplegic arrest remains the method of choice for myocardial protection in cardiac surgery. Caffeic acid phenethyl ester (CAPE) prevents lipid peroxidation induced by ischemia-reperfusion injury and has a potent antioxidant property. We investigated the advantages of CAPE supplemented cardioplegic solution (St. Thomas' Hospital cardioplegic solution No.: 2) on the antioxidant defense system of myocardium against ischemia-reperfusion injury.