CDKN1B mutation analyses and biochemical characteristics in patients with symptomatic or asymptomatic primary hyperparathyroidism

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AKKUŞ G., Coskun N. S. S., Karagun B., TETİKER B. T.

CUKUROVA MEDICAL JOURNAL, vol.47, no.2, pp.852-860, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.17826/cumj.1095425
  • Journal Name: CUKUROVA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.852-860
  • Keywords: Primary Hyperparathyroidism, symptomatic hyperparathyroidism, asymptomatic hyperparathyroidism, ENDOCRINE NEOPLASIA TYPE-1, SURGICAL-MANAGEMENT, LOCALIZATION, HYPERCALCEMIA, SCINTIGRAPHY, GUIDELINES, STATEMENT, CALCIUM, SURGERY, GENES
  • Çukurova University Affiliated: Yes

Abstract

Purpose: The aim of this study was to compare clinical, biochemical and treatment modalities of the patients with symptomatic and asymptomatic PHPT (primary hyperparathyroidism), and evaluate whether the CDKN1B mutation from these patients contributes to the pathogenesis of typical, sporadic parathyroid adenomas.