Evaluating Choroidal Characteristics in Systemic Sclerosis Using Enhanced Depth Imaging Optical Coherence Tomography

ESEN E. , Tas D. A. , SIZMAZ S. , TÜRK İ. , ÜNAL İ. , Demircan N.

OCULAR IMMUNOLOGY AND INFLAMMATION, vol.25, no.3, pp.356-362, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.3109/09273948.2015.1129424
  • Page Numbers: pp.356-362


Purpose: To evaluate choroidal thickness (CT) and investigate the involvement of choroidal circulation in patients with systemic sclerosis (SSc).Methods: A total of 120 eyes of 60 SSc patients and 60 eyes of 30 healthy controls were evaluated. CT measurements were performed at the subfoveal region, 1000 mu m nasal and 1000 mu m temporal to the fovea, using enhanced depth imaging optical coherence tomography. CT measurements were compared between the patients and controls.Results: The average subfoveal, parafoveal nasal and parafoveal temporal CT were significantly thinner in SSc patients when compared with healthy controls (297.77 60.8 mu m vs 339.8 +/- 50.4 mu m; 267.32 +/- 51.1 mu m vs 308.65 +/- 49.9 mu m; 270.63 +/- 46.3 mu m vs 309.22 +/- 42.4 mu m, respectively; p<0.001 for all).Conclusions: Reduced CT in SSc patients supports the hypothesis of widespread vascular injury, including the ocular microcirculation.