Quercetin and Cinnamaldehyde Show Antipathogenic Activity Against Proteus mirabilis Isolates: Inhibition of Swarming Motility and Urease Activity

AYGÜL A., KİBAR F., Ciragil P.

FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, cilt.25, sa.1, ss.76-83, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5578/flora.69001
  • Dergi Adı: FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.76-83
  • Anahtar Kelimeler: Proteus mirabilis, Quercetin, Cinnamaldehyde, Swarming motility, Urease activity, URINARY-TRACT-INFECTIONS, IDENTIFICATION, EXPRESSION, VIRULENCE
  • Çukurova Üniversitesi Adresli: Evet

Özet

Introduction: Antipathogenic molecules target not the vital structures but the virulence factors of pathogenic microorganisms to prevent the development of an infection. Proteus mirabilis is a right candidate for testing antipathogenic molecules due to its distinctive features as an uropathogen such as spreading on urinary catheter surfaces by swarming motility, forming crystalline biofilm by intense urease activity and causing kidney stones.