The effect of levetiracetam on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury

Kilicdag, Hasan; Daghoglu, YUSUF; ERDOĞAN, ŞEYDA; Guzel, Asian; SENCAR, LEMAN; POLAT, SAİT; ZORLUDEMİR, SUZAN

doi:10.1016/j.earlhumdev.2012.12.002

The effect of levetiracetam on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury

Atıf İçin Kopyala

Kilicdag H., Daghoglu K. , ERDOĞAN Ş. , Guzel A., SENCAR L. , POLAT S. , et al.

EARLY HUMAN DEVELOPMENT, cilt.89, ss.355-360, 2013 (SCI İndekslerine Giren Dergi)

Cilt numarası: 89 Konu: 5
Basım Tarihi: 2013
Doi Numarası: 10.1016/j.earlhumdev.2012.12.002
Dergi Adı: EARLY HUMAN DEVELOPMENT
Sayfa Sayısı: ss.355-360

Özet

Background: Hypoxic-ischemic brain injury (HIBI) is a common cause of neonatal mortality and morbidity. The use of levetiracetam (LEV), as a potential neuroprotective in brain ischemia, receives an increasingly high attention, and it could have a crucial role in the regulation of epileptogenesis and neuroprotection. Potential effects of LEV on neuronal apoptosis in HIBI have not previously been reported in literature.