The effect of levetiracetam on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury


Kilicdag H., Daghoglu K. , ERDOĞAN Ş. , Guzel A., SENCAR L. , POLAT S. , ...Daha Fazla

EARLY HUMAN DEVELOPMENT, cilt.89, ss.355-360, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 89 Konu: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.earlhumdev.2012.12.002
  • Dergi Adı: EARLY HUMAN DEVELOPMENT
  • Sayfa Sayıları: ss.355-360

Özet

Background: Hypoxic-ischemic brain injury (HIBI) is a common cause of neonatal mortality and morbidity. The use of levetiracetam (LEV), as a potential neuroprotective in brain ischemia, receives an increasingly high attention, and it could have a crucial role in the regulation of epileptogenesis and neuroprotection. Potential effects of LEV on neuronal apoptosis in HIBI have not previously been reported in literature.