Comparison of blood gas and acid-base measurements in arterial and venous blood samples in patients with uremic acidosis and diabetic ketoacidosis in the emergency room

GOKEL Y., Paydas S., KOSEOGLU Z., ALPARSLAN N., SEYDAOGLU G.

AMERICAN JOURNAL OF NEPHROLOGY, cilt.20, sa.4, ss.319-323, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1159/000013607
  • Dergi Adı: AMERICAN JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.319-323
  • Anahtar Kelimeler: arterial blood gas values, venous blood gas, HCO3-, uremic acidosis, diabetic ketoacidosis, VALUES, PH
  • Çukurova Üniversitesi Adresli: Evet

Özet

Background/aims: The aim of this study was to examine a plausible correlation between venous and arterial blood gas values in acidotic patients with chronic uremia or diabetic ketoacidosis (DKA). Methods: A total of 152 arterial and 152 venous blood samples from uremic patients (n = 100), DKA patients (n = 21) and healthy controls (n = 31) were analyzed for measurements of blood gas and acid-base status. Results: The means of arterial and venous pH, and arterial and venous HCO3- values for the uremic patients were 7.17 +/- 0.14, 7.13 +/- 0.14, 10.13 +/- 4.26 and 11.86 +/- 4.23 mmol/l, respectively. The respective mean differences between arterial and venous pH values and arterial and venous HCO, values were 0.04 +/- 0.02 and -1.72 +/- 0.42 mmol/l, respectively, for these patients. The means of the laboratory findings of DKA patients were arterial pH, 7.15 +/- 0.15; venous pH, 7.10 +/- 0.15; arterial HCO. 8.57 +/- 5.71 mmol/l and venous HCO3-, 10.46 +/- 5.73 mmol/l. The respective mean differences between arterial and venous pH and arterial and venous HCO, for this group were calculated to be 0.05 +/- 0.01 and -1.88 +/- 0.41 mmol/l. In the healthy controls, the means of arterial and venous pH, and arterial and venous HCO, values were 7.39 +/- 0.02, 7.34 +/- 0.02, 24.91 +/- 0.82 and 26.57 +/- 0.83 mmol/l, respectively. For the healthy controls the mean differences between the respective values in arterial and venous pH, and arterial and venous HCO3- were 0.05 +/- 0.01 and -1.66 +/- 0.58 mmol/l. Although in healthy controls the correlation between arterial and venous pH values (r(2): 0.595) and arterial and venous HCO3- values (r(2): 0.552) were moderate, these correlations were significantly increased in both the acidotic patient group (r(2): 0.979 and 0.990) and the DKA group (r(2): 0.989 and 0.995) Conclusion A venous blood sample can be used to evaluate the acid-base status in uremic and DKA patients. Copyright (C) 2000 S. Karger AG, Basel.