Peripheral Nerve Axonal Excitability in Epileptic Patients

Yerdelen D., Koc F.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.30, no.1, pp.108-115, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2013
  • Title of Journal : JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Page Numbers: pp.108-115

Abstract

Introduction: Sodium (Na+) channels have an important role for action potential formation in both central nervous system (CNS) and peripheral nervous system (PNS). The persistent Na+ current play a role in repetitive firing of action potentials caused by prolonged depolarization, thus could play a role in epilepsy. Nerve excitability measurements are made to investigate biophysical properties and disturbances of impulse conduction in peripheral axons in human subjects.