Impact of tumor stage, operative down-staging, tumor grade and radioresponsitivity of the tumor on survival in supratentorial astrocytomas

Erkurt E., Tunali C., Erkisi M., Boyer B., Burgurt R.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, vol.17, no.4, pp.471-478, 1998 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 1998
  • Journal Name: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.471-478
  • Çukurova University Affiliated: No

Abstract

This retrospective study analyzed specifically the predicting factors for radioresponse and survival in 74 supratentorial astrocytoma patients. As a result of this study, cytoreduction in terms of ODs to T1 or TO stage level or pre-RT T1 tumor stage along with radioresponse has a positive impact on long-term survival. It seems that radical radiotherapy should be the choice of treatment for the patients who had pre-RT TO and T1 disease who were found more likely to respond to radiotherapy. This has not been reported previously and needs to be confirmed in larger trials.