Intravenous Paracetamol Overdose A Pediatric Case Report

ASLAN N., YILDIZDAS D., ARSLAN D., HOROZ O. O., YILMAZ H. L., BILEN S.

PEDIATRIC EMERGENCY CARE, vol.35, no.2, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.1097/pec.0000000000001432
  • Journal Name: PEDIATRIC EMERGENCY CARE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: hepatotoxicity, intravenous, overdose, paracetamol, ACETAMINOPHEN, CHILDREN
  • Çukurova University Affiliated: Yes

Abstract

Paracetamol is a common antipyretic often used to treat children with fever and pain. With the increasing administration of intravenous (IV) paracetamol, there will be the associated risk of medication dosing errors. We report a case of IV paracetamol overdose in a child with fever during hospital admission. A IV paracetamol dosing error occurred, with delayed recognition resulting in transient hepatotoxicity, with a peak alanine transaminase of 1946 IU/L and aspartate transaminase of 1633 IU/L.