X=Y-ZH system as potential 1,3-dipoles. Part 59: Cascade 1,3-azaprotio cyclotransfer-1,3-dipolar cycloaddition (1,3-APT-1,3-DC) reactions of benzobicyclo[3.3.1]non-5-en-9-one oxime

DÖNDAŞ, HACI; Fishwick, CWG; Grigg, R; Thornton-Pett, M

doi:10.1016/j.tet.2003.10.027

X=Y-ZH system as potential 1,3-dipoles. Part 59: Cascade 1,3-azaprotio cyclotransfer-1,3-dipolar cycloaddition (1,3-APT-1,3-DC) reactions of benzobicyclo[3.3.1]non-5-en-9-one oxime

Atıf İçin Kopyala

DÖNDAŞ H. A., Fishwick C., Grigg R., Thornton-Pett M.

TETRAHEDRON, cilt.59, sa.50, ss.9997-10007, 2003 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 59 Sayı: 50
Basım Tarihi: 2003
Doi Numarası: 10.1016/j.tet.2003.10.027
Dergi Adı: TETRAHEDRON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.9997-10007
Çukurova Üniversitesi Adresli: Hayır

Özet

Preparation of some novel spiro-oxazolidines related to 3, which is known to posses anorectic and antidepressant activity, via 1,3-APT- 1,3-DC cascades of the oxime of benzobicyclo[3.3. 1]non-5-en-9-one 1 is described. Substrate I allows the influence of the two bridges on the cascade to be assessed with respect to the configuration of the nitrone that is generated and the facial selectivity of the subsequent cycloaddition. (C) 2003 Elsevier Ltd. All rights reserved.