Glucocorticoid sensitivity in Behcet's disease


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Quax R. A. M. , van Laar J. A. M. , van Heerebeek R., Greiner K., Ben-Chetrit E., Stanford M., ...More

ENDOCRINE CONNECTIONS, vol.1, no.2, 2012 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1530/ec-12-0056
  • Title of Journal : ENDOCRINE CONNECTIONS

Abstract

Objective: Glucocorticoid (GC) sensitivity is highly variable among individuals and has been associated with susceptibility to develop (auto-) inflammatory disorders. The purpose of the study was to assess GC sensitivity in Behcet's disease (BD) by studying the distribution of four GC receptor (GR) gene polymorphisms and by measuring in vitro cellular GC sensitivity.