Glucocorticoid sensitivity in Behcet's disease

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Quax R. A. M., van Laar J. A. M., van Heerebeek R., Greiner K., Ben-Chetrit E., Stanford M., ...More

ENDOCRINE CONNECTIONS, vol.1, no.2, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1530/ec-12-0056
  • Journal Name: ENDOCRINE CONNECTIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Çukurova University Affiliated: Yes

Abstract

Objective: Glucocorticoid (GC) sensitivity is highly variable among individuals and has been associated with susceptibility to develop (auto-) inflammatory disorders. The purpose of the study was to assess GC sensitivity in Behcet's disease (BD) by studying the distribution of four GC receptor (GR) gene polymorphisms and by measuring in vitro cellular GC sensitivity.