Recurrent ischemic stroke as an initial manifestation of an concealed pancreatic adenocarcinoma: Trousseau's syndrome

Giray S., Sarica F. B. , Arlier Z., Bal N.

CHINESE MEDICAL JOURNAL, cilt.124, sa.4, ss.637-640, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 124 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3760/cma.j.issn.0366-6999.2011.04.030
  • Sayfa Sayıları: ss.637-640


In rare instances, stroke may preceed a diagnosis of cancer and be the first clinical evidence of an underlying malignancy. Cerebral infarction mostly complicates lymphomas, carcinomas, and solid tumors. Malignancy-related thromboembolism can present as acute cerebral infarction, nonbacterial thrombotic endocarditis and migratory thrombophlebitis. It is generally attributed to a cancer-related hypercoagulable period, chronic dissemiated intravascular coagulopathy (DIC), or tumor embolism. We reported a case of malignancy-releated thromboembolism from an undiagnosed pancreatic adenocarcinoma in a 54-year-old man, who presented with recurrent ischemic stroke due to chronic DIC. He died of the underlying malignancy despite the appropriate institution of anticoagulation therapy.