Resistance artery mechanics and composition in angiotensin II-infused mice: effects of cyclooxygenase-1 inhibition

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Virdis A., Colucci R., Neves M. F., Rugani I., Aydinoglu F., Fornai M., ...More

EUROPEAN HEART JOURNAL, vol.33, no.17, pp.2225-2234, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 17
  • Publication Date: 2012
  • Doi Number: 10.1093/eurheartj/ehr138
  • Journal Name: EUROPEAN HEART JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2225-2234
  • Çukurova University Affiliated: Yes

Abstract

Aims The aim of this study was to investigate the role of cyclooxygenase (COX)-1 on vascular alterations in structure, mechanics, and extracellular matrix (ECM) components induced by angiotensin (Ang) II in mesenteric arteries from wild-type (WT) and COX-1 knockout (COX-1(-/-)) mice.