Solid phase sequential 1,3-dipolar cycloaddition-Pictet-Spengler reactions

DÖNDAŞ H. A., Grigg R., MacLachlan W., MacPherson D., Markandu J., Sridharan V., ...More

TETRAHEDRON LETTERS, vol.41, no.6, pp.967-970, 2000 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 6
  • Publication Date: 2000
  • Doi Number: 10.1016/s0040-4039(99)02183-8
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.967-970
  • Keywords: cycloaddition, Pictet-Spengler reaction, Pd catalysis, cascade reaction, HIGHLY FUNCTIONALIZED PYRROLIDINES, COMBINATORIAL CHEMISTRY, ORGANIC-SYNTHESIS, SUPPORT
  • Çukurova University Affiliated: No


Up to six bonds and two rings can be created, in five component processes (five points of diversity), by AgOAc catalysed imine cycloaddition to Wang resin acrylate followed by Pictet-Splengler and Pd(0) catalysed reactions. (C) 2000 Elsevier Science Ltd. All rights reserved.