Clinical effects of probiotics containing Bacillus species on gingivitis: a pilot randomized controlled trial

Alkaya B., Laleman I., Keceli S., Ozcelik O., HAYTAÇ M. C., Teughels W.

JOURNAL OF PERIODONTAL RESEARCH, vol.52, no.3, pp.497-504, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1111/jre.12415
  • Journal Name: JOURNAL OF PERIODONTAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.497-504
  • Keywords: Bacillus, gingivitis, oral hygiene, probiotics, LACTOBACILLUS-SALIVARIUS WB21, MUTANS STREPTOCOCCI COUNTS, DOUBLE-BLIND, CHRONIC PERIODONTITIS, ORAL MALODOR, REUTERI, HALITOSIS, LOZENGES, TABLETS
  • Çukurova University Affiliated: Yes

Abstract

Background and ObjectiveLactobacillus spp. and bifidobacteria are the most frequently used probiotics in oral health research. However, although probiotic effects have been suggested for other genera, such as bacilli, no trials are available to describe the effect of bacilli probiotics on gingivitis in humans. The aim of the present study was to evaluate the clinical effects of a bacilli-containing toothpaste, a mouthrinse and a toothbrush cleaner versus a placebo in patients with generalized gingivitis.