The present paper investigates the prediction of vibration, noise level, and emission characteristics of a four-stroke, four-cylinder diesel engine fueled with sunflower, canola, and corn biodiesel blends while H-2 injected through inlet manifold using two different artificial intelligence methods: artificial neural network(ANN) and support vector machines(SVM). The aim of using these methods is to predict vibration, noise, carbon monoxide (CO), CO2, and NOx based on the initial experimental study by varying engine speed, blends of biodiesel, and H-2 energy substitution ratio. Experimental data weregathered from the literature. For theANN method, LevenbergMarquardt backpropagation training algorithm with logarithmic sigmoid and linear transfer function for hidden and output layers, respectively, gives the best results for prediction of vibration, noise, and emission characteristics. For SVM, a regression model is implemented with Gaussian kernel function. Results show that the ANN performs better than SVM, and the bestmean average percent error and R-2 for the models developed are 2.03 and 0.988 for vibration acceleration, 0.39 and 0.9615 for noise, 7.27 and 0.8549 for CO, 5.09 and 0.9398 for NOx, and2.21 and 0.993 for CO2 values, respectively. Eventually, it is found that the ANN method is a good choice for simulation and prediction of dual fueled hydrogen sunflower, canola, and corn biodiesel blends.