Cross-aldol reaction of 3-acetyl-2H-chromen-2-one by using Amberlyst 26A as catalyst

Erşatır M. , Akbaşlar D. , Demirkol O. , Giray E. S.

SYNTHETIC COMMUNICATIONS, cilt.47, ss.68-77, 2017 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 47
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/00397911.2016.1252047
  • Sayfa Sayıları: ss.68-77


Synthesis of a series of 3-acetylcoumarin-derived chalcones (1a-16a) was catalyzed with Amberlyst 26A in ethanol. Using reusable Amberlyst 26A and biobased solvent ethanol make this method highly ecofriendly and simple. Amberlyst 26A was found to be a highly effective catalyst for cross aldol reaction. The results shown that the method is operationally simple to implement with a wide scope of substrates.