Physiological and Pathological Effects of Fetal and Maternal Microchimerism.
Current Research in Medical Sciences, cilt.1, sa.1, ss.14-23, 2022 (Hakemli Dergi)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 1 Sayı: 1
- Basım Tarihi: 2022
- Doi Numarası: 10.56397/crms.2022.12.03
- Dergi Adı: Current Research in Medical Sciences
- Sayfa Sayıları: ss.14-23
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Çukurova Üniversitesi Adresli: Evet
Özet
Microchimerism (Mc) is a bidirectional exchange of fetal and maternal cells during pregnancy. Pregnancy
is the most common and natural cause of chimerism. Therefore, we are all born as microchimera. Although there are many unanswered questions it is thought that chimerism has an important role in
human health. For many years, the clinical effects of microchimeric cells (McCs) in organ repair and
cancer therapy have just begun to be understood. While the mission of chimerism is straight forward, the
subject is profound. Chimerism carries the potential for disease as well as for health benefits. This article
describes the role of Mc in the etiology of psychotic disorders. In this review, we consider Mc to be a
physiological phenomenon, but it can also transform into pathology under inappropriate conditions. We
describe in detail below the possible physio-pathological roles of F-MMcCs.