In vitro effect of trimetazine on K-Cl cotransport and superoxide dismutase activity in Hemoglobin SS erythrocytes
PERIODICUM BIOLOGORUM, cilt.107, sa.2, ss.231-234, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 107 Sayı: 2
- Basım Tarihi: 2005
- Dergi Adı: PERIODICUM BIOLOGORUM
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.231-234
- Çukurova Üniversitesi Adresli: Hayır
Özet
Background and Purpose: Trimetazidine (TMZ) (1-2,3,4 trimethoxybenzyl piperazine dihydrochloride) is a cyto-productive agent which is used as an anti-anginal drug. Sickle Cell Anemia (SCA) is characterized by increased K-Cl cotransport (KCC) activity and self-generated free radicals. The aim of study was to investigate the effect of TMZ on KCC activity and free radicals in SCA patients.