Akademik Veri Yönetim Sistemi
COCUK ENFEKSIYON DERGISI, cilt.18, ss.175-183, 2024 (ESCI)
Objective: It is aimed to determine the etiology, clinical features and
short-term prognosis in pediatric patients with fever of unknown origin
(FUO). The study included patients with a history of fever lasting more
than a week with a fever >38.3 °C despite being hospitalized for eight
days and more or examined in the outpatient clinic.
Material and Methods: Study is performed in Adana City Training and
Research Hospital between January 2018-September 2021. Patients’
diseases were investigated in four groups according to etiological causes,
including infectious diseases, non-infectious inflammatory diseases,
malignant diseases and others.
Results: Of 65 patients, 34% were female, 66% were male. Forty percent
of the patients had infectious diseases, while 33.8% were included in the
non-infectious inflammatory diseases group. Sixteen point nine percent
of patients had malignant diseases. The most common infectious disease
was tuberculosis (23%), the most common non-infectious inflammatory
disease was juvenile idiopathic arthritis (JIA) (20%) and leukemia (9.1%).
The shortest mean time of diagnosis was 10 days for infectious diseases.
The group with the least antipyretic response was the malignant group
(27%). Invasive examinations aided the diagnosis of diseases with a rate
of 37%.
Conclusion: Despite advanced diagnostic tests and increasing clinical
experience, FUO is a disease that remains uppermost important, and infectious
diseases rank first among the causes of FUO.