Akademik Veri Yönetim Sistemi
Exposure and Health, 2025 (SCI-Expanded)
Endocrine disrupting chemicals (EDCs) accumulate in the body through various everyday products and disrupt the hormonal system leading to long-term health problems. The aim of this single-arm observational mother–infant dyad study was to investigate exposure to endocrine-disrupting chemicals (EDCs) in mother breast milk, infant faeces, and hair, and to examine their associations with demographic factors, diet, anthropometry, and living standards among a total of 106 participant pairs. 153 EDCs were analyzed by liquid chromatography/tandem mass spectrometry and gas chromatography-electron capture detector. Infants with organochlorine (OC) pesticides in their hair and infants of mothers with organophosphorus (OP) pesticides in their breast milk had lower birth weights compared to those without pesticides (p < 0.05). The mother's involvement in agriculture did not increase the likelihood of pesticide presence; however, infants living near a waste dump/transformer station had a higher likelihood of OP pesticide presence in their hair (p = 0.020). The use of plastic containers and plastic wrap increased diethylhexyl phthalate (DEHP) concentration in infant hair, while the duration of polyvinyl chloride (PVC) and laminate use increased DEHP concentration in mother breast milk (p < 0.05). DEHP were less frequently found in the milk of mothers with older infants (p = 0.017). Flutriafol concentration was observed to be higher in infants with a lower gestational week (p = 0.005). This study will guide future research on EDCs exposure and to develop interventions that reduce health risks.