Reactivation rates in patients using biological agents, with resolved HBV infection or isolated anti-HBc IgG positivity


SOLAY A. H., ACAR A., ESER F., KUŞCU F., TUTUNCU E. E., KUL G., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.29, no.5, pp.561-565, 2018 (SCI-Expanded, Scopus, TRDizin)

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.5152/tjg.2018.18032
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.561-565
  • Çukurova University Affiliated: Yes

Abstract

Background/Aims: Tumor necrosis factor-alpha (TNF-alpha) inhibitors and ustekunimab are widely used in autoimmune diseases. It is known that these biological agents cause the reactivation of hepatitis 8 virus (HBV). There is no standardized strategy to prevent the reactivation in patients with evidence of a previous HBV infection. In our study, anti-HBc IgG-positive patients who received a biological agent were evaluated in terms of HBV reactivation.