Motor neuron disease associated with multiple myeloma

Koc F., Paydas S., Yerdelen D., Demirkiran M.

INTERNATIONAL JOURNAL OF NEUROSCIENCE, cilt.118, sa.3, ss.337-341, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 118 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1080/00207450701242644
  • Dergi Adı: INTERNATIONAL JOURNAL OF NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.337-341
  • Anahtar Kelimeler: motor neuron disease, Multiple myeloma, AMYOTROPHIC-LATERAL-SCLEROSIS, LYMPHOPROLIFERATIVE DISORDERS, MACROGLOBULINEMIA, PARAPROTEINEMIA, ANTIBODIES, LYMPHOMA
  • Çukurova Üniversitesi Adresli: Evet

Özet

The association between Amyotrophic Lateral Sclerosis or other Motor Neuron Diseases (MNDs) with Lymphoproliferative Disorders (LPDs) and plasma cell neoplasias (such as Hodgkin's or non-Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, multiple myeloma, chronic lymphocytic leukemia) has been described. It is not clear whether LPDs play a role in the pathogenesis of MND; however it is possible that patients might have antibodies against motor neurons. An association between motor neuron disease and Multiple myeloma (MM) is rarely reported in the literature. This article reports a case of a 75-year-old male with MM and MND. Interestingly, the patient was in complete remission for MM when he was diagnosed as MND and he died due to progressive MND.