Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency

Kiykim, Ayca; Öğülür, İsmail; Dursun, Esra; Charbonnier, Louis; Nain, Ercan; Çekiç, Şükrü; Doğruel, DİLEK; Karaca, Neslihan; Çöğürlü, Müjde; Bilir, Ozlem; Cansever, Murat; Kapakli, Hasan; Baser, Dilek; Kasap, Nurhan; Kutluğ, Şeyhan; Altıntaş, DERYA; Al-Shaibi, Ahmad; Agrebi, Nourhen; Kara, Manolya; Guven, Ayla; Somer, Ayper; Aydogmus, Cigdem; Ayaz, Nuray; Metin, Ayse; Aydoğan, Metin; Uncuoğlu, Ayşen; Patiroglu, Turkan; Yıldıran, Alişan; Güner, Şükrü; Keleş, Sevgi; Reisli, İsmail; Aksu, Güzide; Kütükçüler, Necil; Kilic, Sara; Yılmaz, MUSTAFA; Karakoc-Aydiner, Elif; Lo, Bernice; Ozen, Ahmet; Chatila, Talal; Barış, Safa

doi:10.1016/j.jaip.2019.06.011

Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency

Atıf İçin Kopyala

Kiykim A., Öğülür İ., Dursun E., Charbonnier L. M., Nain E., Çekiç Ş., ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, cilt.7, ss.2790-2815, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.jaip.2019.06.011
Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2790-2815
Çukurova Üniversitesi Adresli: Evet

Özet

BACKGROUND: LPS-responsive beige-like anchor (LRBA) deficiency presents with susceptibility to infections, autoimmunity, and lymphoproliferation. The long-term efficacy of cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin (abatacept) as targeted therapy for its immune dysregulatory features remains to be established.