Application areas of 3D bioprinting


OZBOLAT I. T. , PENG W., ÖZBOLAT V.

DRUG DISCOVERY TODAY, cilt.21, ss.1257-1271, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 21 Konu: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.drudis.2016.04.006
  • Dergi Adı: DRUG DISCOVERY TODAY
  • Sayfa Sayısı: ss.1257-1271

Özet

Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.