Alport's syndrome with bilateral macular hole

Mete U. Ö., Karaaslan C., Ozbilgin M., Polat S., Tap O., Kaya M.

ACTA OPHTHALMOLOGICA SCANDINAVICA, vol.74, no.1, pp.77-80, 1996 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 1
  • Publication Date: 1996
  • Journal Name: ACTA OPHTHALMOLOGICA SCANDINAVICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Page Numbers: pp.77-80
  • Keywords: Alport's syndrome, bilateral macular hole, anterior lenticonus, retinal flecks ultrastructure, OCULAR MANIFESTATIONS, LENTICONUS, GENETICS
  • Çukurova University Affiliated: Yes

Abstract

In this study 8 patients with Alport's syndrome are presented. The ocular manifestations of these patients were retinal flecks, macular depigmentation, microspherophakia and anterior lenticonus. One patient revealed bilateral macular hole which was an unusual feature. Four patients had renal biopsies with the characteristic electron microscopic changes of the disease, According to these findings our conclusion is that Alport's syndrome is a disorder of selected basement membranes.