Decreased glutathione levels in acute myocardial infarction

Usal A., Acarturk E., Yuregir G., Unlukurt I., Demirci C., Kurt H., et al.

JAPANESE HEART JOURNAL, cilt.37, ss.177-182, 1996 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 37 Konu: 2
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1536/ihj.37.177
  • Dergi Adı: JAPANESE HEART JOURNAL
  • Sayfa Sayısı: ss.177-182

Özet

Although experimental studies have demonstrated that reduced glutathione (GSH) is involved in cellular protection from deleterious effects of oxygen free radicals (OFRs) in ischemia and reperfusion, there are controversial data on the correlation between the levels of erythrocyte GSH and the ischemic process. To clarify, we determined the erythrocyte GSH levels in 21 patients with acute myocardial infarction (AIL?I), aged 39-70, who were not given thrombolytic therapy and 21 age- and sex- matched healthy controls. Samples of blood were taken on days 1, 3, 5 and 7 from AMI patients and on the same days from the controls.