Role of hypoxia and embryonic stem cell genes in head and neck cancers

ILGAZ N. S., Oksuz H., Yilmaz M. B., Keser N., ALPTEKİN D.

CUKUROVA MEDICAL JOURNAL, vol.47, no.1, pp.7-15, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.17826/cumj.978648
  • Journal Name: CUKUROVA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.7-15
  • Keywords: Head and neck cancers, hypoxia, embryonic stem cell marker, HIF, ESTROGEN-RELATED RECEPTOR, ALPHA ERR-ALPHA, INVERSE AGONIST, PROSTATE-CANCER, EXPRESSION, GROWTH, HIF-2-ALPHA, PROLIFERATION, HIF-1-ALPHA, BIOLOGY
  • Çukurova University Affiliated: Yes

Abstract

Purpose: The aim of this study was to determine the effect of hypoxia on HIF-1 alpha, HIF-2 alpha, SOX2, OCT4, NANOG, CD133, ESRRA genes in Hep-2 laryngeal and FaDu pharyngeal cancer cell lines.