Risk of developing fibroadenoma with the use of cyclosporine A in renal transplant recipients


BINOKAY F. , BALAL M., DEMIR E. , Paydas S. , SOYUPAK S. , SERTDEMIR Y. , et al.

RENAL FAILURE, cilt.27, ss.721-725, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/08860220500243197
  • Dergi Adı: RENAL FAILURE
  • Sayfa Sayısı: ss.721-725

Özet

To investigate the effect of cyclosporine A (Cyc A) on the development of fibroadenomas, 30 renal transplant patients and 20 chronic renal failure patients on dialysis were breast examined with ultrasonography and/or mammography. Of the renal transplant patients, 17 were receiving Cyc A-based combination therapy for immunosuppression. All patients were female with the age range of 29.7 +/- 9.2 years in the transplant group and 33.95 +/- 9.91 in the dialysis group. Eight of the 17 patients receiving Cyc A had fibroadenomas, 5 of them having bilateral lesions. None of the other patients, those on dialysis and on non-Cyc A combination therapy had fibroadenomas. A significant difference for fibroadenoma incidence in patients receiving Cyc A combination immunosuppression was found.