Is concomitant high CD7 and low pRB expression associated with central nervous system involvement in acute leukemia?


Sahin B., Paydas S., Hazar B.

CANCER JOURNAL, vol.9, no.4, pp.192-195, 1996 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 4
  • Publication Date: 1996
  • Title of Journal : CANCER JOURNAL
  • Page Numbers: pp.192-195

Abstract

Background - Central nervous system (CNS) involvement is an adverse prognostic factor in potentially curable leukemic patients and a frequent feature in certain CD7(+) acute leukemias, Our aim was to investigate whether low expression of retinoblastoma gene product (pRB) and high expression of CD7 could have any association with CNS involvement in acute leukemias.