Is concomitant high CD7 and low pRB expression associated with central nervous system involvement in acute leukemia?


Sahin B., Paydas S., Hazar B.

CANCER JOURNAL, cilt.9, ss.192-195, 1996 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 9 Konu: 4
  • Basım Tarihi: 1996
  • Dergi Adı: CANCER JOURNAL
  • Sayfa Sayıları: ss.192-195

Özet

Background - Central nervous system (CNS) involvement is an adverse prognostic factor in potentially curable leukemic patients and a frequent feature in certain CD7(+) acute leukemias, Our aim was to investigate whether low expression of retinoblastoma gene product (pRB) and high expression of CD7 could have any association with CNS involvement in acute leukemias.