Akademik Veri Yönetim Sistemi
Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, cilt.52, sa.1, ss.8-12, 2019 (Hakemli Dergi)
INTRODUCTION: There are still controversies in the literatureregarding the role of corticosteroids in the treatment of HELLPsyndrome. The aim of this study is to investigate the effect ofdexamethasone treatment on maternal outcome.MATERIALS AND METHODS: The study included 20 patientswho were followed in ICU with the diagnosis of HELLP syndrome.Data regarding the age, gestational age, Mississippi class, APACHEII score, hematologic and biochemical measurements, mortality andlength of ICU stay were analyzed retrospectively.RESULTS: Two patients died due to the multiple organ failure.Twelve patient received dexamethasone treatment (Group 1) andeight patients did not receive steroid treatment (Group 2). There wasnot any statistically significant difference in the length of ICU stay,mortality, and transfusion requirements between the groups. Thepatients receiving dexamethasone treatment showed an increasedimprovement in platelet count; however the difference was notstatistically significant.CONCLUSIONS: Dexamethasone treatment did not result in anyimprovement in mortality, length of ICU stay, and in the plateletcounts in patients with HELLP syndrome.