Serum free carnitine levels in epileptic children on valproic acid

Altunbasak S., Artar O., Yildizdas D., Ozbarlas N., Kayrin L., Burgut R.

3rd European Congress of Epileptology, Warszawa, Polonya, 24 - 28 Mayıs 1998, ss.33-38 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası:
  • Basıldığı Şehir: Warszawa
  • Basıldığı Ülke: Polonya
  • Sayfa Sayıları: ss.33-38
  • Çukurova Üniversitesi Adresli: Evet

Özet

This study was carried out in a multipupose-based design to evaluate serum-free carnitine (SFC) levels in epileptic children. In a three-stage model, we sought to determine (a) SFC levels in epileptic patients receiving Valproic acid (WA) or other antiepileptic drugs for at least sir months, (b) on a longitudinal basis, WA-induced alterations in SFC levels in new cases given VPA therapy, and (c) whether decreased SFC levels were associated with detoriation in myocardial and respiratory functions and whether and to what extent use of L-carnitine supplementation would be justified to counter the presumable myocardial dysfunction.