Effects of lisinopril, atenolol, and isosorbide 5-mononitrate on angina pectoris and QT dispersion in patients with syndrome X: An open-label, randomized, crossover study


Kanadasi M., Demir M., Demirtas M., Akpinar O., Alhan C.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.63, sa.4, ss.273-283, 2002 (SCI-Expanded) identifier identifier

Özet

Background: The triad of angina pectoris, a positive exercise electrocardiographic test, and a normal coronary angiogram is described as syndrome X. Because the definite underlying pathophysiologic mechanism of syndrome X is not fully understood, there is no consensus about its treatment. It has been suggested that the prolonged QT interval observed in patients with syndrome X is due to autonomic nervous system dysfunction.