Effects of lisinopril, atenolol, and isosorbide 5-mononitrate on angina pectoris and QT dispersion in patients with syndrome X: An open-label, randomized, crossover study


Kanadasi M., Demir M., Demirtas M., Akpinar O., Alhan C.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, vol.63, no.4, pp.273-283, 2002 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 4
  • Publication Date: 2002
  • Doi Number: 10.1016/s0011-393x(02)80032-7
  • Title of Journal : CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
  • Page Numbers: pp.273-283

Abstract

Background: The triad of angina pectoris, a positive exercise electrocardiographic test, and a normal coronary angiogram is described as syndrome X. Because the definite underlying pathophysiologic mechanism of syndrome X is not fully understood, there is no consensus about its treatment. It has been suggested that the prolonged QT interval observed in patients with syndrome X is due to autonomic nervous system dysfunction.