Limbic encephalitis with antibodies to glutamic acid decarboxylase presenting with brainstem symptoms

İNCECİK F., Herguner O. M., Yildizdas D., Horoz O., BESEN S.

ANNALS OF INDIAN ACADEMY OF NEUROLOGY, vol.18, no.2, pp.243-245, 2015 (SCI-Expanded) identifier identifier identifier


Limbic encephalitis (LE) is a neurological syndrome that may present in association with cancer, infection, or as an isolate clinical condition often accompanying autoimmune disorders. LE associated with glutamic acid decarboxylase antibodies (anti-GAD) is rare in children. Here, we characterized the clinical and laboratory features of a patient presenting with brainstem involvement with non-paraneoplastic LE associated with anti-GAD antibodies. In our patient, after plasma exchange, we determined a dramatic improvement of the neurological deficits.