In this research, the mediating role of hope in the relation between high school students' life goals and career adaptability was examined. The study has been carried out with 353 high school students (195 girls, 158 boys). The mean age of the students was 16.05. The data have been collected by using "Career Adapt-Abilities Scale", "Life Goals Scale for Adolescents" and "Dispositional Hope Scale". The collected data was analyzed through correlation analysis, path analysis and, bootstrapping procedure for the significance of indirect effect test. As a result of the study suggest that career goals, body-sense goals, hope has a positively meaningful relation with career adaptability. Bootstrapping show that hope have a partial mediating role in the relation between career goals, body-sense goals and career adaptability. It is thought that the results obtained can be used to improve the career adaptability of high school students. In addition, it can be said that the results of the research will provide the basis for future studies.