Acute-phase reactants and cytokines in ischemic stroke: do they have any relationship with short-term mortality?

SAHAN M., SEBE A., Acikalin A., AKPINAR O., KOC F., AY M. O., ...More

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.17, no.20, pp.2773-2777, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 20
  • Publication Date: 2013
  • Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2773-2777
  • Keywords: Acute-phase reactant, Cytokine, Emergency, Mortality, Stroke, C-REACTIVE PROTEIN, STRONG PREDICTORS, RISK, INFLAMMATION, FIBRINOGEN, LEUKOCYTES, MARKERS, WOMEN
  • Çukurova University Affiliated: Yes

Abstract

BACKGROUND: Many unknown risk factors play a role in the etiopathogenesis of stroke. The appearance of inflammatory cells within the damaged tissue after cerebral ischemia suggests that an inflammatory response may play a role in stroke pathogenesis. In our study, we examined whether an association exists between the acute-phase reactants and the levels of cytokines, the volume and diameter of the stroke, and short-term mortality in patients who were diagnosed as acute ischemic a stroke after admission to the Emergency Department.