The effects of infusion of perineural pregabalin in the experimentally created sciatic nerve anastomosis in rats


Civi S., Bulduk E. B. , Kocer N. E. , Kardes O., Suner H. I. , Durdag E., ...More

ANNALI ITALIANI DI CHIRURGIA, vol.89, no.5, pp.465-471, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 5
  • Publication Date: 2018
  • Title of Journal : ANNALI ITALIANI DI CHIRURGIA
  • Page Numbers: pp.465-471

Abstract

INTRODUCTION AND OBJECT: The aim of our study was to assess the effect of perineural pregabalin administration on the success of coaptation in experimental rat sciatic nerve anastomosis by measuring the expression of anti-inflammatory cytokine TGF-beta. It is thus to provide alternative solutions to this problem which we often see in clinical practice and whose results are not satisfactory.